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Yayın Co-array optimization of CMUT arrays for forward-looking IVUS(IEEE, 2009-09) Tekeş, Coşkun; Karaman, Mustafa; Değertekin, Fahrettin LeventThe ring annular array structure is a preferred configuration for implementing Forward-Looking IVUS (FLIVUS) catheters as it allows for volumetric imaging as well as use of a guidewire at the center. CMUT technology is promising for these arrays especially with the flexibility of locating array elements on the circular donut area efficiently. To take advantage of this flexibility, in this study, we introduce a new co-array sampling strategy that improves imaging performance while keeping the number of firings at a level suitable for real-time imaging. The presented co-array sampling strategy is based on the idea of adjusting the element density of the co-array rings in radial direction to suppress side lobes. In non-uniform sampling of the co-array with a given number of firings, the inter-element distances are adjusted both in radial and angular direction from inner ring to outer ring to fit a given apodization function. To test the imaging performance, we performed numerical simulations of the co-array with non-uniform sampling fitting to the raised-cosine apodization. The simulation results shows that sidelobe level can be reduced more than 10 dB by using non-uniform co-array sampling. This approach does use uniform weighting of all Tx and Rx elements in beamforming, and hence does not cause any SNR loss for apodization.Yayın CMUT-based volumetric ultrasonic imaging array design for forward looking ICE and IVUS applications(SPIE-Int Soc Optical Engineering, 2013) Tekeş, Coşkun; Zahorian, Jaime S.; Xu, Toby; Rashid, Muhammad Wasequr; Satır, Sarp; Gürün, Gökçe; Karaman, Mustafa; Hasler, Jennifer Olson; Değertekin, Fahrettin LeventDesigning a mechanically flexible catheter based volumetric ultrasonic imaging device for intravascular and intracardiac imaging is challenging due to small transducer area and limited number of cables. With a few parallel channels, synthetic phased array processing is necessary to acquire data from a large number of transducer elements. This increases the data collection time and hence reduces frame rate and causes artifacts due to tissue-transducer motion. Some of these drawbacks can be resolved by different array designs offered by CMUT-on-CMOS approach. We recently implemented a 2.1-mm diameter single chip 10 MHz dual ring CMUT-on-CMOS array for forward looking ICE with 64-transmit and 56-receive elements along with associated electronics. These volumetric arrays have the small element size required by high operating frequencies and achieve sub mm resolution, but the system would be susceptible to motion artifacts. To enable real time imaging with high SNR, we designed novel arrays consisting of multiple defocused annular rings for transmit aperture and a single ring receive array. The annular transmit rings are utilized to act as a high power element by focusing to a virtual ring shaped line behind the aperture. In this case, image reconstruction is performed by only receive beamforming, reducing total required firing steps from 896 to 14 with a trade-off in image resolution. The SNR of system is improved more than 5 dB for the same frequency and frame rate as compared to the dual ring array, which can be utilized to achieve the same resolution by increasing the operating frequency.Yayın Evaluation of CMUT annular arrays for side-looking IVUS(IEEE, 2009) Şişman, Alper; Zahorian, Jaime S.; Gürün, Gökçe; Karaman, Mustafa; Balantekin, Müjdat; Değertekin, Fahrettin Levent; Hasler, Paul E.Side-looking (SL) IVUS probes are extensively used for management of cardiovascular diseases. Currently SL-IVUS imaging probes use either a single rotating transducer element or solid-state arrays. Probes with single rotating piezoelectric transducer have simple front-end, but have fixed focused operation, and suffers from motion artifacts. Solid-state SL-IVUS imaging probes use piezoelectric transducer arrays and electronic beam-forming. Synthetic phased array processing of signals detected with small-sized elements in these arrays limits the SNR achievable with these probes. In this study, we explore a new SL-IVUS probe architecture employing rotating phased annular CMUT arrays. We tested and compared imaging performance of the existing and proposed probe configurations through simulated point spread functions. We also two fabricated sample annular array designs operating at 20-MHz and 50-MHz. Our experimental measurements on the 20-MHz array in oil shows 105% fractional bandwidth. The 50-MHz array with parylene coating shows approximately 40% fractional bandwidth measured in water. We also present imaging results acquired from wire-targets to test the experimental point-spread functions.Yayın Optimizing circular ring arrays for forward-looking IVUS imaging(IEEE-Inst Electrical Electronics Engineers Inc, 2011-12) Tekeş, Coşkun; Karaman, Mustafa; Değertekin, Fahrettin LeventForward-looking (FL) catheter-based imaging systems are highly desirable for guiding interventions in intravascular ultrasound (IVUS) applications. One of the main challenges of array-based FL-IVUS systems is the large channel count, which results in increased system complexity. Synthetic phased-array processing with a reduced firing count simplifies the front-end and, hence, can enable 3-D real-time imaging. Recently, we have investigated dual-ring arrays suitable for IVUS imaging, in which the two concentric circular arrays are used separately as transmit (Tx) and receive (Rx) arrays. In this study, we present different optimized array designs based on dual and single circular rings which are suitable for synthetic phased-array processing with a reduced number of firings. To obtain an optimal firing set that produces low side lobes in the wideband response, we use a simulated annealing algorithm. In the simulations, we use 1.2-mm-diameter array configurations with 64 Tx and 58 Rx elements, a center frequency of 20 MHz and fractional bandwidths of 50% and 80%. The results show that optimized dual-ring arrays provide 8 dB improvements in peak near side-lobe level with no widening in the main lobe width when compared with full and other sparse co-arrays.Yayın Dual-annular-ring CMUT array for forward-looking IVUS imaging(IEEE, 2006) Güldiken, Rasim Oytun; Zahorian, Jaime; Balantekin, Müjdat; Değertekin, Fahrettin Levent; Tekeş, Coşkun; Şişman, Alper; Karaman, MustafaWe investigate a dual-annular-ring CMUT array configuration for forward-looking intravascular ultrasound (FL-IVUS) imaging. The array consists of separate, concentric transmit and receive ring arrays built on the same silicon substrate. This configuration has the potential for independent optimization of each array and uses the silicon area more effectively without any particular drawback. We designed and fabricated a 1mm diameter test array which consists of 24 transmit and 32 receive elements. We investigated synthetic phased array beamforming with a non-redundant subset (if transmit-receive element pairs of the dual-annular-ring array. For imaging experiments, we designed and constructed a programmable FPGA-based data acquisition and phased array beamforming system. Pulse-echo measurements along with imaging simulations suggest that dual-ring-annular array should provide performance suitable for real-time FLAVUS applications.Yayın Experimental study of dual-ring CMUT array optimization for forward-looking IVUS(IEEE, 2011) Tekeş, Coşkun; Zahorian, Jaime; Gürün, Gökçe; Satir, Sarp; Hochman, Michael; Xu, Toby; Rashid, Muhammad Wasequr; Değertekin, Fahrettin Levent; Karaman, MustafaForward-looking (FL) catheters have guiding and volumetric imaging capacities which are highly desirable for IVUS applications. Large channel and firing counts have to be reduced to enable 3-D real-time imaging and simplify front-end electronics. Recently, we have proposed an optimization procedure for dual ring FL arrays which is based on finding an optimal coarray set using the simulated annealing algorithm. The presented algorithm is based on finding a predefined number of optimal firing set which results in elimination of redundant spatial frequencies in the coarray. In this study, we present the experimental demonstration of the proposed method with fabricated single chip CMUT on CMOS system based FL dual ring arrays. The dual ring CMUT arrays were monolithically fabricated on top of CMOS chips which have 25-V pulsers and low-noise transimpedance amplifiers for each transmit and receive array elements. The fabricated CMUT arrays have 56 transmit and 48 receive elements operating at 12 MHz with a 1.4 mm outer diameter. To test the imaging performance of the optimal reduced set, we obtained a 512-element coarray set from the full 2688-element set. In the experiment, we used a phantom of 100-mu m aluminium wires immersed in oil tank. We have reconstructed both 2-D PSFs and B-scan images of wire targets. Experimental results demonstrate that the simulated annealing based optimal firing set achieves acceptable lateral and contrast resolution performances with 1/5 of the full set.Yayın Forward-looking IVUS imaging using a dual-annular ring CMUT array: Experimental results(IEEE, 2007) Güldiken, Rasim Oytun; Zahorian, Jaime S.; Gürün, Gökçe; Qureshi, Muhammad Shakeel; Balantekin, Müjdat; Tekeş, Coşkun; Hasler, Paul E.; Karaman, Mustafa; Carlier, Stephane; Değertekin, Fahrettin LeventThis paper presents the experimental results on forward-looking Intravascular ultrasound (FL-IVUS) using dual-annular-ring CMUT arrays. The array has a diameter of 1mm including bondpads which consists of separate, concentric 24 transmit and 32 receive ring arrays built on the same silicon substrate. This configuration has the potential for Independent optimization of each array and uses the silicon area more effectively without any drawback. For imaging experiments, we designed and constructed a custom integrated circuit using a standard 0.5 mu m CMOS process for data acquisition. A sample pulse-echo signal received from the oil-air Interface (plane reflector) at 6mm had a center frequency of 11MHz with 95% fractional 6-dB bandwidth. The measured SNR of the echo was 24 dB with no averaging. B-scan image of a wire-phantom was generated to test the resolution.Yayın Annular-ring CMUT arrays for forward-looking IVUS: Transducer characterization and imaging(IEEE, 2006-02) Değertekin, Fahrettin Levent; Güldiken, Rasim Oytun; Karaman, MustafaIn this study, a 64-element, 1.15-mm diameter annular-ring capacitive micromachined ultrasonic transducer (CMUT) array was characterized and used for forward-looking intravascular ultrasound (IVUS) imaging tests. The array was manufactured using low-temperature processes suitable for CMOS electronics integration oil a single chip. The measured radiation pattern of a 43 X 140- mu m(2) array element depicts a 40 degrees view angle for forward-looking imaging around a 15-MHz center frequency in agreement with theoretical models. Pulse-echo measurements show a -10-dB fractional bandwidth of 104% around 17 MHz for wire targets 2.5 mm away from the array in vegetable oil. For imaging and SNR measurements, RF A-scan data sets from various targets were collected using all interconnect scheme forming a 32-element array configuration. An experimental point spread function was obtained and compared with simulated and theoretical array responses, showing good agreement. Therefore, this study demonstrates that annular-ring CMUT arrays fabricated with CMOS-compatible processes are capable of forward-looking IVUS imaging, and the developed modeling tools can be used to design improved IVUS imaging arrays.Yayın An analog integrated circuit beamformer for high-frequency medical ultrasound imaging(IEEE-INST Electrical Electronics Engineers Inc, 2012-10) Gürün, Gökçe; Zahorian, Jaime S.; Şişman, Alper; Karaman, Mustafa; Hasler, Paul E.; Değertekin, Fahrettin LeventWe designed and fabricated a dynamic receive beamformer integrated circuit (IC) in 0.35-mu m CMOS technology. This beamformer IC is suitable for integration with an annular array transducer for high-frequency (30-50 MHz) intravascular ultrasound (IVUS) imaging. The beamformer IC consists of receive preamplifiers, an analog dynamic delay-and-sum beamformer, and buffers for 8 receive channels. To form an analog dynamic delay line we designed an analog delay cell based on the current-mode first-order all-pass filter topology, as the basic building block. To increase the bandwidth of the delay cell, we explored an enhancement technique on the current mirrors. This technique improved the overall bandwidth of the delay line by a factor of 6. Each delay cell consumes 2.1-mW of power and is capable of generating a tunable time delay between 1.75 ns to 2.5 ns. We successfully integrated the fabricated beamformer IC with an 8-element annular array. Experimental test results demonstrated the desired buffering, preamplification and delaying capabilities of the beamformer.
