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  • Yayın
    Graph convolutional network based virus-human protein-protein interaction prediction for novel viruses
    (Elsevier Ltd, 2022-08-13) Koca, Mehmet Burak; Nourani, Esmaeil; Abbasoğlu, Ferda; Karadeniz, İlknur; Sevilgen, Fatih Erdoğan
    Computational identification of human-virus protein-protein interactions (PHIs) is a worthwhile step towards understanding infection mechanisms. Analysis of the PHI networks is important for the determination of path-ogenic diseases. Prediction of these interactions is a popular problem since experimental detection of PHIs is both time-consuming and expensive. The available methods use biological features like amino acid sequences, molecular structure, or biological activities for prediction. Recent studies show that the topological properties of proteins in protein-protein interaction (PPI) networks increase the performance of the predictions. The basic network projections, random-walk-based models, or graph neural networks are used for generating topologically enriched (hybrid) protein embeddings. In this study, we propose a three-stage machine learning pipeline that generates and uses hybrid embeddings for PHI prediction. In the first stage, numerical features are extracted from the amino acid sequences using the Doc2Vec and Byte Pair Encoding method. The amino acid embeddings are used as node features while training a modified GraphSAGE model, which is an improved version of the graph convolutional network. Lastly, the hybrid protein embeddings are used for training a binary interaction classifier model that predicts whether there is an interaction between the given two proteins or not. The proposed method is evaluated with comprehensive experiments to test its functionality and compare it with the state-of-art methods. The experimental results on the benchmark dataset prove the efficiency of the proposed model by having a 3–23% better area under curve (AUC) score than its competitors.
  • Yayın
    BOUN-ISIK participation: an unsupervised approach for the named entity normalization and relation extraction of Bacteria Biotopes
    (Association for Computational Linguistics (ACL), 2019-11-04) Karadeniz, İlknur; Tuna, Ömer Faruk; Özgu, Arzucan
    This paper presents our participation at the Bacteria Biotope Task of the BioNLP Shared Task 2019. Our participation includes two systems for the two subtasks of the Bacteria Biotope Task: the normalization of entities (BB-norm) and the identification of the relations between the entities given a biomedical text (BB-rel). For the normalization of entities, we utilized word embeddings and syntactic re-ranking. For the relation extraction task, pre-defined rules are used. Although both approaches are unsupervised, in the sense that they do not need any labeled data, they achieved promising results. Especially, for the BB-norm task, the results have shown that the proposed method performs as good as deep learning based methods, which require labeled data.
  • Yayın
    TurkEmbed: Turkish embedding model on natural language inference & sentence text similarity tasks
    (Institute of Electrical and Electronics Engineers Inc., 2025) Ezerceli, Özay; Gümüşçekiçci, Gizem; Erkoç, Tuğba; Özenç, Berke
    This paper introduces TurkEmbed, a novel Turkish language embedding model designed to outperform existing models, particularly in Natural Language Inference (NLI) and Semantic Textual Similarity (STS) tasks. Current Turkish embedding models often rely on machine-translated datasets, potentially limiting their accuracy and semantic understanding. TurkEmbed utilizes a combination of diverse datasets and advanced training techniques, including matryoshka representation learning, to achieve more robust and accurate embeddings. This approach enables the model to adapt to various resource-constrained environments, offering faster encoding capabilities. Our evaluation on the Turkish STS-b-TR dataset, using Pearson and Spearman correlation metrics, demonstrates significant improvements in semantic similarity tasks. Furthermore, TurkEmbed surpasses the current state-of-the-art model, Emrecan, on All-NLI-TR and STS-b-TR benchmarks, achieving a 1-4% improvement. TurkEmbed promises to enhance the Turkish NLP ecosystem by providing a more nuanced understanding of language and facilitating advancements in downstream applications.
  • Yayın
    Narrative conflicts: a tri-modal computational analysis of antagonism in Shakespeare’s Julius Caesar
    (CEUR-WS, 2025-09-26) Yavuz, Mehmet Can; Cascone, Lucia; Özkan, Aylin; Ertaş, İrem
    This study introduces a novel computational framework to analyze multi-modal antagonisms—semantic, emotional, and relational—in dramatic literature, specifically focusing on Shakespeare’s Julius Caesar. Employing natural language processing (NLP) techniques, text embeddings, emotion classifiers, and network-based character analyses, we systematically extract and quantify antagonistic relationships within the play. Semantic antagonisms are identified through hierarchical clustering and dimensionality reduction of character embeddings, revealing rhetorical groupings aligned closely with narrative functions. Emotional antagonisms, captured via emotion distribution profiles and variance analysis, illuminate characters’ affective dynamics and their alignment with dramatic roles. Relational antagonisms are explored through co-occurrence networks, highlighting unexpected centrality of minor characters as critical mediators of conflict. Integrating these modalities with Hegelian dialectics and Nietzschean interpretations, our tri-modal analysis provides fresh insights into ideological tensions, character motivations, and narrative structure. This interdisciplinary approach demonstrates the effectiveness of AI-driven tools in enriching literary criticism opening new avenues for exploring conflict dynamics in canonical texts.