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Yayın Integrated ultrasonic imaging systems based on CMUT arrays: Recent progress(IEEE, 2004) Wygant, Ira O.; Zhuang, Xuefeng; Yeh, David T.; Nikoozadeh, Amin; Oralkan, Ömer; Ergün, Arif Sanlı; Karaman, Mustafa; Khuri-Yakub, Butrus ThomasThis paper describes the development of an ultrasonic imaging system based on a two-dimensional capacitive micromachined ultrasonic transducer (CMUT) array. The transducer array and front-end electronics are designed to fit in a 5-mm endoscopic channel. A custom-designed integrated circuit, which comprises the front-end electronics, will be connected with the transducer elements via through-wafer interconnects and flip-chip bonding. FPGA-based signal-processing hardware will provide real-time three-dimensional imaging. The imaging system is being developed to demonstrate a means of integrating the front-end electronics with the transducer array and to provide a clinically useful technology. Integration of the electronics can improve signal-to-noise ratio, reduce the number of cables connecting the imaging probe to a separate processing unit, and provide a means of connecting electronics to large two-dimensional transducer arrays. This paper describes the imaging system architecture and the progress we have made on implementing each of its components: a 16×16 CMUT array, custom-designed integrated circuits, a flip-chip bonding technique, and signal-processing hardware.Yayın Evaluation of CMUT annular arrays for side-looking IVUS(IEEE, 2009) Şişman, Alper; Zahorian, Jaime S.; Gürün, Gökçe; Karaman, Mustafa; Balantekin, Müjdat; Değertekin, Fahrettin Levent; Hasler, Paul E.Side-looking (SL) IVUS probes are extensively used for management of cardiovascular diseases. Currently SL-IVUS imaging probes use either a single rotating transducer element or solid-state arrays. Probes with single rotating piezoelectric transducer have simple front-end, but have fixed focused operation, and suffers from motion artifacts. Solid-state SL-IVUS imaging probes use piezoelectric transducer arrays and electronic beam-forming. Synthetic phased array processing of signals detected with small-sized elements in these arrays limits the SNR achievable with these probes. In this study, we explore a new SL-IVUS probe architecture employing rotating phased annular CMUT arrays. We tested and compared imaging performance of the existing and proposed probe configurations through simulated point spread functions. We also two fabricated sample annular array designs operating at 20-MHz and 50-MHz. Our experimental measurements on the 20-MHz array in oil shows 105% fractional bandwidth. The 50-MHz array with parylene coating shows approximately 40% fractional bandwidth measured in water. We also present imaging results acquired from wire-targets to test the experimental point-spread functions.Yayın Dual-annular-ring CMUT array for forward-looking IVUS imaging(IEEE, 2006) Güldiken, Rasim Oytun; Zahorian, Jaime; Balantekin, Müjdat; Değertekin, Fahrettin Levent; Tekeş, Coşkun; Şişman, Alper; Karaman, MustafaWe investigate a dual-annular-ring CMUT array configuration for forward-looking intravascular ultrasound (FL-IVUS) imaging. The array consists of separate, concentric transmit and receive ring arrays built on the same silicon substrate. This configuration has the potential for independent optimization of each array and uses the silicon area more effectively without any particular drawback. We designed and fabricated a 1mm diameter test array which consists of 24 transmit and 32 receive elements. We investigated synthetic phased array beamforming with a non-redundant subset (if transmit-receive element pairs of the dual-annular-ring array. For imaging experiments, we designed and constructed a programmable FPGA-based data acquisition and phased array beamforming system. Pulse-echo measurements along with imaging simulations suggest that dual-ring-annular array should provide performance suitable for real-time FLAVUS applications.Yayın Damar içi öne bakan ultrasonik görüntüleme için eşdeğer dizi örnekleme yöntemleri(IEEE, 2009-06-26) Tekeş, Coşkun; Karaman, MustafaDamar içi öne bakan ultrasonik görüntüleme gerçek zamanlı hacimsel (üç boyutlu) görüntülemeye imkan vermesi bakımından yaygın olarak kullanılmaktadır. Damar içi görüntülemede fiziksel boyutların küçük olması nedeniyle alıcı-verici kanal sayısı çok sınırlanmakta ve dolayısıyla yapay evreli dizi teknikleri kullanılmaktadır. Öte yandan, harekete bağlı görüntü bozukluklarını azaltmak için işaret gönderme alma adım sayısının azaltılması gerekmektedir. Bu, eşdeğer dizideki fazlalık frekans bileşenleri azaltılarak sağlanabilir. Bu çalışmada, eşdeğer dizideki fazlalık frekans bileşenlerinin azaltılmasına dayalı farklı örnekleme teknikleri incelenmiştir. Bu tekniklerin görüntü kalitesi 64 elemanlı bir halkasal dizinin asıl ve kontrol eşdeğer dizileri referans alınarak karşılaştırmalı olarak irdelenmiştir. Benzetim sonuçları 64 elemanlı bir halka dizi için 2049 asıl küme, 350 azaltılmış küme 40 dB içinde eşdeğer performans vermektedir.Yayın Subarray delta-sigma beamforming for ultrasonic imaging(IEEE, 2002) Bilge, Hasan Şakir; Karaman, MustafaWe present a beamforming architecture based on subarray processing with non-uniform oversampling 1-bit delta-sigma (??) modulation. The subarray processing combines conventional phased array and synthetic aperture approaches to form a large aperture using small subarrays thus reduces active channel count. ??-based beamforming improves the efficiency of front-end processing further: oversampling permits precise delaying and single bit data processing simplifies beamforming operation. To reduce the number of firings we use a low beam density associated with the subarray size, and then increase the beam density by lateral interpolation prior to coherent beam summation. Our experimental test results show that the proposed scheme provides high-resolution beamforming while simplifying the front-end.Yayın Volumetric imaging using fan-beam scanning with reduced redundancy 2D arrays(IEEE, 2006) Wygant, Ira; Karaman, Mustafa; Oralkan, Ömer; Khuri-Yakub, Butrus ThomasPhased array processing with a fully populated 2D array produces the best image quality but requires excessive number of active parallel front-end channels. Here we explore four array designs with reduced redundancy in spatial frequency contents. To minimize the number of firings we employ fan-beam processing, where ID arrays are used to insonify 2D planar slices of the volume at successive firing events; echo signals are collected by the receive array elements. The array designs are compared based on simulated point spread functions, frame rate, motion susceptibility, and signal-to-noise ratio.Yayın An integrated circuit with transmit beamforming and parallel receive channels for real-time three-dimensional ultrasound imaging(IEEE, 2006) Wygant, Ira O.; Lee, Hyunjoo J.; Nikoozadeh, Amin; Yeh, David T.; Oralkan, Ömer; Karaman, Mustafa; Khuri-Yakub, Butrus ThomasWe present the design of an integrated circuit (IC) that will be flip-chip bonded to a 16 x 16-element CMUT array. The IC provides 16 receive channels which can be configured to receive along either of the array diagonals or on any single row of the array. On transmit, all 256 elements can be used to transmit arbitrarily focused beams. Focused transmission with the full array is made possible by on-chip pulsers and memory. A 25-V pulser and 8-bit shift register is provided for each element of the array. Prior to each transmit, new values are loaded into the shift registers. Current-con trolled one-shots control the transmit pulse widths. Circuit simulations and the IC layout are presented. Simulations predict that delay values can be loaded in less than 1.3 mu s and show the generation of precisely timed pulses. The IC is being prepared for submission to National Semiconductor for fabrication in a high-voltage BiCMOS process.Yayın An integrated circuit with transmit beamforming and parallel receive channels for 3D ultrasound imaging: testing and characterization(IEEE, 2007) Wygant, Ira O.; Jamal, Nafis S.; Lee, Hyunjoo J.; Nikoozadeh, Amin; Zhuang, Xuefeng; Oralkan, Ömer; Ergün, Arif Sanlı; Karaman, Mustafa; Khuri-Yakub, Butrus ThomasThe cost and complexity of medical ultrasound imaging systems can be reduced by integrating the transducer array with an integrated circuit (IC). By incorporating some of the system's front-end electronics into an IC, bulky cables and costly system electronics can be eliminated. Here we present an IC for 3D intracavital imaging that requires few electrical connections but uses a large fraction of a 16x16-element 2D transducer array to transmit focused ultrasound. To simplify the receive and data acquisition electronics, only the 32 elements along the array diagonals are used as receivers. The IC provides a preamplifier for each receiving element. Each of the 224 transmitting elements is provided an 8-bit shift register, a comparator, and a 25-V pulser. To transmit, a global counter is incremented from 1 to 224; each pulser fires when its stored register value is equal to the global count value. Electrical testing of the fabricated IC shows that it works as designed. The IC was flip-chip bonded to a two-dimensional capacitive micromachined ultrasonic transducer (CMUT) array. A two-dimensional image of a wire target phantom was acquired.Yayın A tunable analog delay element for high-frequency dynamic beamforming(IEEE, 2009) Gürün, Gökçe; Şişman, Alper; Zahorian, Jaime S.; Satır, Sarp; Karaman, Mustafa; Hasler, Paul E.; Değertekin, Fahrettin LeventImplementing beamforming for high frequency arrays is challenging because of the accurate delay requirements at high frequencies. High frequency digital beamforming is not suitable for catheter based applications as a large number of cables is required between the array and the external beamformer. A possible solution is to perform analog beamforming on an integrated circuit adjacent or monolithically integrated to the imaging array. In this study, we introduce an improved voltage in voltage out low pass filter as an analog delay cell for high frequency dynamic beamformers. This circuit can generate three times more delay with a given bandwidth when compared to conventional low pass filters. Delay of the circuit is tunable and the gain of the cell is inherently very close to unity. The proposed delay cell operates single ended and therefore is more suitable for CMUT operation which generates single ended output. We designed a test beamformer for a 30MHz, equal area, annular array with 100% bandwidth using the proposed delay cell and the unit-delay focusing architecture. Required delays are implemented using a delay line made up of improved delay elements with tunable delays. To demonstrate functionality we designed and fabricated a custom front-end IC in a 0.5µm standard CMOS process. The IC chip consists of 8 transimpedance amplifiers, voltage-to-current converters, the analog dynamic beamformer, and two buffers. We present results of preliminary imaging experiments that demonstrate the focusing capability.
