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Yayın Olanzapin kullanımına bağlı çekilme diskinezisi ve süpersensitivite psikozu(Turkish Neuropsychiatric Society, 2016-06) Karaş, Hakan; Güdük, Mehmet; Saatçioğlu, İbrahim ÖmerTardive dyskinesia (TD) usually appears after years of antipsychotic drug use and appears to be related to the total lifetime medication dose. In withdrawal-emergent dyskinesia (WE-D), which is considered to be a subtype of TD, dyskinetic symptoms often appear shortly after a rapid reduction in antipsychotic drug dose or sudden discontinuation of the drug. Supersensitivity psychosis, which is frequently observed along with TD and is considered to have a similar etiology as TD, is a psychotic relapse phenomenon that occurs after the withdrawal of an antipsychotic drug or a rapid reduction in the drug dosage. In general, atypical antipsychotics tend to be associated with less propensity to cause TD when compared with typical antipsychotics. Furthermore, olanzapine and clozapine may have a therapeutic potential in improving or totally curing TD. In this study, a case of WE-D because of discontinuing olanzapine use and supersensitivity psychosis is discussed.Yayın The comparison of functional connectivity in Parkinson’s Disease patients with and without Parkin gene mutations(Turkish Neuropsychiatric Society, 2025-06-19) Çebi, Merve; Ay, Ulaş; Kıçik, Ani; Erdoğdu, Emel; Tepgeç, Fatih; Uyguner, Zehra Oya; Tüfekçioğlu, Zeynep; Samancı, Bedia; Bilgiç, Başar; Emre, Murat; Demiralp, Tamer; Hanağası, Haşmet AyhanIntroduction: Mapping the functional connectivity of brain regions became appealing in recent research in neurology. Accordingly, a growing body of evidence shows resting-state functional connectivity (rsFC) changes in neurodegenerative disorders including Parkinson’s Disease (PD). As characterised by extensive and progressive dopaminergic loss in the substantia nigra, PD emerges with serious motor and non-motor dysfunctions. In the literature, the minority of PD cases have been associated with certain genetic mutations. The aim of this study was to investigate the rsFC in a group of PD patients having Parkin gene mutation. Method: Twelve PD patients with Parkin mutation (PP-PD), 12 PD patients without Parkin mutation (PN-PD) and 12 healthy controls (HC) were included in the study. All participants underwent a resting-state functional magnetic resonance imaging as well as a neuropsychological assessment and clinical examination. Results: Results indicated that PP-PD had longer disease duration, a higher rate of dyskinesia and lower scores on complex visual perception tests. The resting state networks showed that all PD (consisting of PP-PD and PN-PD) and PP-PD groups had increased functional connectivity in the frontoparietal network as compared to the HC. In addition, the PP-PD group displayed decreased functional connectivity in the dorsal attention network compared to the PN-PD. Conclusion: In conclusion, our data suggests that PD with Parkin gene mutation might be emerging with distinct resting state functional connectivity changes in the brain.Yayın The relationship between conflict management styles used by nurse managers in psychiatric clinics and the stress level of their subordinates(Kare Publishing, 2025-06-30) Çabuk, Merve; Acuner, DenizObjectives: This study aimed to determine the relationship between the opinions of nurses working in psychiatric wards regarding their managers' conflict management styles and their self-perceived stress levels. Methods: This was a descriptive, comparative, and correlational study. The population consisted of 580 nurses working in psychiatric clinics of public and private hospitals in Istanbul, and 199 nurses were included in the sample. The "Personal Information Form," "Rahim Organizational Conflict Inventory–II (ROCI-II) Form A," and "Perceived Stress Scale" were used for data collection. Data were analyzed using frequency and percentage distributions, the Kruskal–Wallis test, Spearman correlation analysis, and the Mann–Whitney U test. Results: The participants’ mean scores on the Conflict Management Scale were as follows: integration subscale 2.50±0.90; obliging subscale 3.03±0.74; dominating subscale 2.92±0.85; avoiding subscale 2.98±0.66; and compromising subscale 2.61±0.83. The mean score of the Perceived Stress Scale was 13.78±4.74. The mean score for the perceived stress subdimension was 4.49±2.04, and for the perceived coping subdimension was 9.30±3.45. A statistically significant, weak positive correlation was found between the perceived stress subdimension and the dominating subscale, while a weak negative correlation was observed with the compromising and integration subdimensions. A weak negative correlation was also found between the perceived coping subdimension and the integration, obliging, and compromising subdimensions. Conclusion: According to the nurses, their managers most frequently use obliging, avoiding, dominating, compromising, and integration styles, respectively, in conflict management. As managers’ use of compromising and integration styles increases, the nurses’ perceived stress levels decrease.
