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Yayın Integrated ultrasonic imaging systems based on CMUT arrays: Recent progress(IEEE, 2004) Wygant, Ira O.; Zhuang, Xuefeng; Yeh, David T.; Nikoozadeh, Amin; Oralkan, Ömer; Ergün, Arif Sanlı; Karaman, Mustafa; Khuri-Yakub, Butrus ThomasThis paper describes the development of an ultrasonic imaging system based on a two-dimensional capacitive micromachined ultrasonic transducer (CMUT) array. The transducer array and front-end electronics are designed to fit in a 5-mm endoscopic channel. A custom-designed integrated circuit, which comprises the front-end electronics, will be connected with the transducer elements via through-wafer interconnects and flip-chip bonding. FPGA-based signal-processing hardware will provide real-time three-dimensional imaging. The imaging system is being developed to demonstrate a means of integrating the front-end electronics with the transducer array and to provide a clinically useful technology. Integration of the electronics can improve signal-to-noise ratio, reduce the number of cables connecting the imaging probe to a separate processing unit, and provide a means of connecting electronics to large two-dimensional transducer arrays. This paper describes the imaging system architecture and the progress we have made on implementing each of its components: a 16×16 CMUT array, custom-designed integrated circuits, a flip-chip bonding technique, and signal-processing hardware.Yayın An Analog beamformer for integrated high-frequency medical ultrasound imaging(IEEE, 2011) Gürün, Gökçe; Zahorian, Jaime; Tekeş, Coşkun; Karaman, Mustafa; Hasler, Paul E.; Değertekin, Fahrettin LeventWe designed and fabricated a dynamic receive beamforming integrated circuit (IC) in 0.35-mu m CMOS technology. This beamformer is suitable for integration with an ultrasound annular array for high-frequency (30-50 MHz) intravascular ultrasound (IVUS) imaging. The beamformer IC is capable of buffering, delaying and preamplification for 8 receive channels. We explored an analog delay cell based on a currentmode first-order all-pass filter, which is used as the basic building block to form an analog dynamic delay line. We also explored a bandwidth enhancement method on the delay cell that improved the overall bandwidth of the delay line by a factor of 6. Each delay cell consumes 2.1 mW of power and is capable of generating a tunable delay between 1.75 ns to 2.5 ns, enabling dynamic receive beamforming over a focal range from 1.4 mm to 2 mm. We successfully integrated the fabricated beamformer IC with an 8-element annular array. Our experimental test results demonstrated the desired buffering, preamplification and delaying capabilities of the beamformer.Yayın Forward-viewing CMUT arrays for medical Imaging(IEEE-INST Electrical Electronics Engineers Inc, 2004-07) Demirci, Utkan; Ergün, Arif Sanlı; Oralkan, Ömer; Karaman, Mustafa; Khuri-Yakub, Butrus ThomasThis paper reports the design and testing of forward-viewing annular arrays fabricated using capacitive micromachined ultrasonic transducer (CMUT) technology. Recent research studies have shown that CMUTs have broad frequency bandwidth and high-transduction efficiency. One- and two-dimensional CMUT arrays of various sizes already have been fabricated, and their viability for medical imaging applications has been demonstrated. We fabricated 64-element, forward-viewing annular arrays using the standard CMUT fabrication process and carried out experiments to measure the operating frequency, bandwidth, and transmit/receive efficiency of the array elements. The annular array elements, designed for imaging applications in the 20 MHz range, had a resonance frequency of 13.5 MHz in air. The immersion pulse-echo data collected from a plane reflector showed that the devices operate in the 5-26 MHz range with a fractional bandwidth of 135%. The output pressure at the surface of the transducer was measured to be 24 kPa/V. These values translate into a dynamic range of 131.5 dB for I-V excitation in 1-Hz bandwidth with a commercial low noise receiving circuitry. The designed, forward-viewing annular CMUT array is suitable for mounting on the front surface of a cylindrical catheter probe and can provide Doppler information for measurement of blood flow and guiding information for navigation through blood vessels in intravascular ultrasound imaging.Yayın Monolithic CMUT-on-CMOS integration for intravascular ultrasound applications(IEEE-INST Electrical Electronics Engineers Inc, 2011-12) Zahorian, Jaime S.; Hochman, Michael; Xu, Toby; Satır, Sarp; Gürün, Gökçe; Karaman, Mustafa; Değertekin, Fahrettin LeventOne of the most important promises of capacitive micromachined ultrasonic transducer (CMUT) technology is integration with electronics. This approach is required to minimize the parasitic capacitances in the receive mode, especially in catheter-based volumetric imaging arrays, for which the elements must be small. Furthermore, optimization of the available silicon area and minimized number of connections occurs when the CMUTs are fabricated directly above the associated electronics. Here, we describe successful fabrication and performance evaluation of CMUT arrays for intravascular imaging on custom-designed CMOS receiver electronics from a commercial IC foundry. The CMUT-on-CMOS process starts with surface isolation and mechanical planarization of the CMOS electronics to reduce topography. The rest of the CMUT fabrication is achieved by modifying a low-temperature micromachining process through the addition of a single mask and developing a dry etching step to produce sloped sidewalls for simple and reliable CMUT-to-CMOS interconnection. This CMUT-to-CMOS interconnect method reduced the parasitic capacitance by a factor of 200 when compared with a standard wire-bonding method. Characterization experiments indicate that the CMUT-on-CMOS elements are uniform in frequency response and are similar to CMUTs simultaneously fabricated on standard silicon wafers without electronics integration. Experiments on a 1.6-mm-diameter dual-ring CMUT array with a center frequency of 15 MHz show that both the CMUTs and the integrated CMOS electronics are fully functional. The SNR measurements indicate that the performance is adequate for imaging chronic total occlusions located 1 cm from the CMUT array.Yayın Damar içi öne bakan ultrasonik görüntüleme için eşdeğer dizi örnekleme yöntemleri(IEEE, 2009-06-26) Tekeş, Coşkun; Karaman, MustafaDamar içi öne bakan ultrasonik görüntüleme gerçek zamanlı hacimsel (üç boyutlu) görüntülemeye imkan vermesi bakımından yaygın olarak kullanılmaktadır. Damar içi görüntülemede fiziksel boyutların küçük olması nedeniyle alıcı-verici kanal sayısı çok sınırlanmakta ve dolayısıyla yapay evreli dizi teknikleri kullanılmaktadır. Öte yandan, harekete bağlı görüntü bozukluklarını azaltmak için işaret gönderme alma adım sayısının azaltılması gerekmektedir. Bu, eşdeğer dizideki fazlalık frekans bileşenleri azaltılarak sağlanabilir. Bu çalışmada, eşdeğer dizideki fazlalık frekans bileşenlerinin azaltılmasına dayalı farklı örnekleme teknikleri incelenmiştir. Bu tekniklerin görüntü kalitesi 64 elemanlı bir halkasal dizinin asıl ve kontrol eşdeğer dizileri referans alınarak karşılaştırmalı olarak irdelenmiştir. Benzetim sonuçları 64 elemanlı bir halka dizi için 2049 asıl küme, 350 azaltılmış küme 40 dB içinde eşdeğer performans vermektedir.Yayın Design of a third generation real-time cellular neural network emulator(IEEE, 2014) Yıldız, Nerhun; Cesur, Evren; Tavşanoğlu, Ahmet VedatIn this paper, the features of the next generation Real-Time Cellular Neural Network Processor (RTCNNP-v3) are discussed. The RTCNNP-v2 structure is the only CNN implementation that is reported to be capable of processing full-HD 1080p@60 (1920 x 1080 resolution at 60 Hz frame rate) video images in real-time, due to its fully-pipelined architecture, however, it has some weaknesses like the inability to divide the processing in spatial domain, record and recall intermediate results to an external memory and has some issues in its internal memory coding. Those shortcomings are to be addressed in the next design of our CNN emulator - RTCNNP-v3, which will increase the range of applications and enable the implementation to match the requirements of the cutting-edge movie production technologies like UHD (4K) and the future FUHD (8K).Yayın Coherent array imaging using phased subarrays. Part II: Simulations and experimental results(IEEE-INST Electrical Electronics Engineers Inc, 2005-01) Johnson, Jeremy A.; Oralkan, Ömer; Ergün, Arif Sanlı; Demirci, Utkan; Karaman, Mustafa; Khuri-Yakub, Butrus ThomasThe basic principles and theory of phased subarray (PSA) imaging imaging provides the flexibility of reducing I he number of front-end hardware channels between that of classical synthetic aperture (CSA) imaging-which uses only one element per firing event-and full-phased array (FPA,) imaging-which uses all elements for each firing. The performance of PSA generally ranges between that obtained by CSA and FPA using the same array, and depends on the amount of hardware complexity reduction. For the work described in this paper, we performed FPA, CSA, and PSA imaging of a resolution phantom using both simulated and experimental data from a 3-MHz, 3.2-cm, 128-element capacitive micromachined ultrasound transducer (CMUT) array. The simulated system point responses in the spatial and frequency domains are presented as a means of studying the effects of signal bandwidth, reconstruction filter size, and subsampling rate on the PSA system performance. The PSA and FPA sector-scanned images were reconstructed using the wideband experimental data with 80% fractional bandwidth, with seven 32-element subarrays used for PSA imaging. The measurements on the experimental sector images indicate that, at the transmit focal zone, the PSA method provides a 10% improvement in the 6-dB lateral resolution, and the axial point resolution of PSA imaging is identical to that of FPA imaging. The signal-to-noise ratio (SNR) of PSA image was 58.3 dB, 4.9 dB below that of the FPA image, and the contrast-to-noise ratio (CNR) is reduced by 10%. The simulated and experimental test results presented in this paper validate theoretical expectations and illustrate the flexibility of PSA imaging as a way to exchange SNR and frame rate for simplified front-end hardware.Yayın Annular-ring CMUT arrays for forward-looking IVUS: Transducer characterization and imaging(IEEE, 2006-02) Değertekin, Fahrettin Levent; Güldiken, Rasim Oytun; Karaman, MustafaIn this study, a 64-element, 1.15-mm diameter annular-ring capacitive micromachined ultrasonic transducer (CMUT) array was characterized and used for forward-looking intravascular ultrasound (IVUS) imaging tests. The array was manufactured using low-temperature processes suitable for CMOS electronics integration oil a single chip. The measured radiation pattern of a 43 X 140- mu m(2) array element depicts a 40 degrees view angle for forward-looking imaging around a 15-MHz center frequency in agreement with theoretical models. Pulse-echo measurements show a -10-dB fractional bandwidth of 104% around 17 MHz for wire targets 2.5 mm away from the array in vegetable oil. For imaging and SNR measurements, RF A-scan data sets from various targets were collected using all interconnect scheme forming a 32-element array configuration. An experimental point spread function was obtained and compared with simulated and theoretical array responses, showing good agreement. Therefore, this study demonstrates that annular-ring CMUT arrays fabricated with CMOS-compatible processes are capable of forward-looking IVUS imaging, and the developed modeling tools can be used to design improved IVUS imaging arrays.Yayın An integrated circuit with transmit beamforming and parallel receive channels for real-time three-dimensional ultrasound imaging(IEEE, 2006) Wygant, Ira O.; Lee, Hyunjoo J.; Nikoozadeh, Amin; Yeh, David T.; Oralkan, Ömer; Karaman, Mustafa; Khuri-Yakub, Butrus ThomasWe present the design of an integrated circuit (IC) that will be flip-chip bonded to a 16 x 16-element CMUT array. The IC provides 16 receive channels which can be configured to receive along either of the array diagonals or on any single row of the array. On transmit, all 256 elements can be used to transmit arbitrarily focused beams. Focused transmission with the full array is made possible by on-chip pulsers and memory. A 25-V pulser and 8-bit shift register is provided for each element of the array. Prior to each transmit, new values are loaded into the shift registers. Current-con trolled one-shots control the transmit pulse widths. Circuit simulations and the IC layout are presented. Simulations predict that delay values can be loaded in less than 1.3 mu s and show the generation of precisely timed pulses. The IC is being prepared for submission to National Semiconductor for fabrication in a high-voltage BiCMOS process.Yayın An integrated circuit with transmit beamforming and parallel receive channels for 3D ultrasound imaging: testing and characterization(IEEE, 2007) Wygant, Ira O.; Jamal, Nafis S.; Lee, Hyunjoo J.; Nikoozadeh, Amin; Zhuang, Xuefeng; Oralkan, Ömer; Ergün, Arif Sanlı; Karaman, Mustafa; Khuri-Yakub, Butrus ThomasThe cost and complexity of medical ultrasound imaging systems can be reduced by integrating the transducer array with an integrated circuit (IC). By incorporating some of the system's front-end electronics into an IC, bulky cables and costly system electronics can be eliminated. Here we present an IC for 3D intracavital imaging that requires few electrical connections but uses a large fraction of a 16x16-element 2D transducer array to transmit focused ultrasound. To simplify the receive and data acquisition electronics, only the 32 elements along the array diagonals are used as receivers. The IC provides a preamplifier for each receiving element. Each of the 224 transmitting elements is provided an 8-bit shift register, a comparator, and a 25-V pulser. To transmit, a global counter is incremented from 1 to 224; each pulser fires when its stored register value is equal to the global count value. Electrical testing of the fabricated IC shows that it works as designed. The IC was flip-chip bonded to a two-dimensional capacitive micromachined ultrasonic transducer (CMUT) array. A two-dimensional image of a wire target phantom was acquired.












