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Listeleniyor 1 - 8 / 8
  • Yayın
    A stochastic risk-averse framework for blood donation appointment scheduling under uncertain donor arrivals
    (Springer, 2020-12) Yalçındağ, Semih; Baş Güre, Seda; Carello, Giuliana; Lanzarone, Ettore
    Blood is a key resource in all health care systems, usually drawn from voluntary donors. We focus on the operations management in blood collection centers, which is a key step to guarantee an adequate blood supply and a good quality of service to donors, by addressing the so-called Blood Donation Appointment Scheduling problem. Its goal is to employ appointment scheduling to balance the production of blood units between days, in order to provide a reasonably constant supply to transfusion centers and hospitals, and reduce non-alignments between physicians' working times and donor arrivals at the collection center. We consider a two-phase solution framework taken from the literature, in which a deterministic linear programming model preallocates time slots to different blood types and a prioritization policy assigns the preallocated slots to the donors when they make a reservation. However, the problem is stochastic in nature and requires consideration of the uncertain arrivals of non-booked donors. In this work, to include the uncertain arrivals, we propose three stochastic counterparts of the preallocation model based on a risk-neutral objective and two risk-averse objectives, respectively, where the Conditional Value-at-Risk is considered as the risk measure in the last two methods. The resulting stochastic frameworks have been tested considering the historical data of one of the largest Italian collection centers, the Milan Department of the "Associazione Volontari Italiani Sangue" (AVIS). Results show the effectiveness of the stochastic models, especially the mean-risk one, and the need to include the uncertainty of arrivals in order to better balance the production of blood units.
  • Yayın
    P-T phase diagram for NH4F
    (Editions Scientifiques Medicales Elsevier, 2002-04) Salihoğlu, Selami; Yurtseven, Hasan Hamit; Enginer, Yücel
    In this study we obtain a P-T phase diagram of NH4F using the mean-field theory. We fit our calculated phase line equations to the experimental P-T phase diagram. By choosing appropriately the coefficients in the free-energy expansions. our calculated phase diagram agrees well with the experimentally observed phase diagram of NH4F.
  • Yayın
    Collective victimhood beliefs among majority and minority groups: Links to ingroup and outgroup attitudes and attribution of responsibility for conflict
    (Pergamon-Elsevier Science Ltd, 2018-09) Bağcı Hemşinlioğlu, Sabahat Çiğdem; Piyale, Zeynep Ecem; Karaköse Çelik, Selin; Şen, Ezgi
    We examined perceived ingroup and outgroup victimhood beliefs across group status and how these were uniquely associated with ingroup and outgroup attitudes and attribution of responsibility among majority (Turkish, N = 141) and minority (Kurdish, N = 86) group members in Turkey. We further explored whether the extent to which collective victimhood beliefs were shared via ingroup and outgroup members predicted our dependent measures beyond the subjective perception of ingroup victimhood. Findings showed that both groups perceived higher ingroup victimhood compared to outgroup victimhood and this difference was more pronounced among the minority group. Perceived outgroup victimhood beliefs, compared to ingroup victimhood beliefs, were more closely related to intergroup outcomes, and led to more positive outgroup and more negative ingroup outcomes. Both groups shared collective victimhood beliefs more with their ingroup friends than their outgroup friends and ingroup sharing of collective victimhood was a stronger predictor of intergroup outcomes, relating to more positive ingroup and more negative outgroup outcomes. Outgroup sharing of collective victimhood was related to more positive outgroup attitudes and lower ingroup responsibility among the Turkish group, whereas it was not related to outgroup attitudes and negatively related to ingroup attribution of responsibility among the Kurdish group. Practical and theoretical implications of the findings were discussed.
  • Yayın
    Forward-viewing CMUT arrays for medical Imaging
    (IEEE-INST Electrical Electronics Engineers Inc, 2004-07) Demirci, Utkan; Ergün, Arif Sanlı; Oralkan, Ömer; Karaman, Mustafa; Khuri-Yakub, Butrus Thomas
    This paper reports the design and testing of forward-viewing annular arrays fabricated using capacitive micromachined ultrasonic transducer (CMUT) technology. Recent research studies have shown that CMUTs have broad frequency bandwidth and high-transduction efficiency. One- and two-dimensional CMUT arrays of various sizes already have been fabricated, and their viability for medical imaging applications has been demonstrated. We fabricated 64-element, forward-viewing annular arrays using the standard CMUT fabrication process and carried out experiments to measure the operating frequency, bandwidth, and transmit/receive efficiency of the array elements. The annular array elements, designed for imaging applications in the 20 MHz range, had a resonance frequency of 13.5 MHz in air. The immersion pulse-echo data collected from a plane reflector showed that the devices operate in the 5-26 MHz range with a fractional bandwidth of 135%. The output pressure at the surface of the transducer was measured to be 24 kPa/V. These values translate into a dynamic range of 131.5 dB for I-V excitation in 1-Hz bandwidth with a commercial low noise receiving circuitry. The designed, forward-viewing annular CMUT array is suitable for mounting on the front surface of a cylindrical catheter probe and can provide Doppler information for measurement of blood flow and guiding information for navigation through blood vessels in intravascular ultrasound imaging.
  • Yayın
    Anti-tobacco control industry strategies in Turkey
    (BioMed Central Ltd, 2018-02-26) Keklik, Seda; Gültekin Karakas, Derya
    Background: Transnational tobacco companies (TTCs) penetrated the Turkish cigarette market due to trade and investment liberalization in the post-1980 period and eventually secured full control. Despite tobacco control policies put in place in reaction to accelerating consumption, TTCs reinforced their market power through a variety of strategies. This paper explores industry strategies that counteract tobacco control policies in Turkey. Methods: The study employs both qualitative and quantitative analyses to explore industry strategies in Turkey. Besides the content analyses of industry and market reports, descriptive analyses were conducted for the sub-periods of 1999-2015. The analyses focus on the market strategies of product innovation, advertisement-promotion, cost management and pricing. Results: Rising sales of low tar, ultra-low tar, slim, super-slim and flavoured cigarettes indicate that product innovation served to sustain consumption. Besides, the tobacco industry, using its strong distribution channels, the Internet, and CSR projects, were found to have promoted smoking indirectly. The industry also rationalized manufacturing facilities and reduced the cost of tobacco, making Turkey a cigarette-manufacturing base. Tobacco manufacturers, moreover, offered cigarettes in different price segments and adjusted net prices both up and down according to price categories and market conditions. In response to the successful effect of shifts in price margins, the market share of mid-priced cigarettes expanded while those within the economy category maintained the highest market share. As a result of pricing strategies, net sales revenues increased. Aside from official cigarette sales, the upward trends in the registered and unregistered sales of cigarette substitutes indicate that the demand-side tobacco control efforts remain inadequate. Conclusions: The Turkish case reveals that the resilience of the tobacco industry vis-a-vis mainstream tobacco control efforts necessitates a new policy perspective. Rising market concentration by TTCs and the global nature of industry strategies require that the highly profitable manufacturing and trade of tobacco products should be discouraged on a basis of international collaboration. To reduce and eventually eradicate tobacco consumption, supply-side tobacco control measures are needed along with demand-side policies.
  • Yayın
    An adaptive locally connected neuron model: Focusing neuron
    (Elsevier B.V., 2021-01-02) Tek, Faik Boray
    This paper presents a new artificial neuron model capable of learning its receptive field in the topological domain of inputs. The experiments include tests of focusing neuron networks of one or two hidden layers on synthetic and well-known image recognition data sets. The results demonstrated that the focusing neurons can move their receptive fields towards more informative inputs. In the simple two-hidden layer networks, the focusing layers outperformed the dense layers in the classification of the 2D spatial data sets. Moreover, the focusing networks performed better than the dense networks even when 70% of the weights were pruned. The tests on convolutional networks revealed that using focusing layers instead of dense layers for the classification of convolutional features may work better in some data sets.
  • Yayın
    Quantum Zeno repeaters
    (Nature Research, 2022-09-12) Bayrakçı, Veysel; Özaydın, Fatih
    Quantum repeaters pave the way for long-distance quantum communications and quantum Internet, and the idea of quantum repeaters is based on entanglement swapping which requires the implementation of controlled quantum gates. Frequently measuring a quantum system affects its dynamics which is known as the quantum Zeno effect (QZE). Beyond slowing down its evolution, QZE can be used to control the dynamics of a quantum system by introducing a carefully designed set of operations between measurements. Here, we propose an entanglement swapping protocol based on QZE, which achieves almost unit fidelity. Implementation of our protocol requires only simple frequent threshold measurements and single particle rotations. We extend the proposed entanglement swapping protocol to a series of repeater stations for constructing quantum Zeno repeaters which also achieve almost unit fidelity regardless of the number of repeaters. Requiring no controlled gates, our proposal reduces the quantum circuit complexity of quantum repeaters. Our work has potential to contribute to long distance quantum communications and quantum computing via quantum Zeno effect.
  • Yayın
    Analyzing language ability in first-episode psychosis and their unaffected siblings: a diffusion tensor imaging tract-based spatial statistics analysis study
    (Elsevier Ltd, 2024-11) Çabuk, Tuğçe; Şahin Çevik, Didenur; Çakmak, Işık Batuhan; Yılmaz Kafalı, Helin; Şenol, Bedirhan; Avcı, Hanife; Karlı Oğuz, Kader; Toulopoulou, Timothea
    Schizophrenia (SZ) is a highly heritable mental disorder, and language dysfunctions play a crucial role in diagnosing it. Although language-related symptoms such as disorganized speech were predicted by the polygenic risk for SZ which emphasized the common genetic liability for the disease, few studies investigated possible white matter integrity abnormalities in the language-related tracts in those at familial high-risk for SZ. Also, their results are not consistent. In this current study, we examined possible aberrations in language-related white matter tracts in patients with first-episode psychosis (FEP, N = 20), their siblings (SIB, N = 20), and healthy controls (CON, N = 20) by applying whole-brain Tract-Based Spatial Statistics and region-of-interest analyses. We also assessed language ability by Thought and Language Index (TLI) using Thematic Apperception Test (TAT) pictures and verbal fluency to see whether the scores of these language tests would predict the differences in these tracts. We found significant alterations in language-related tracts such as inferior longitudinal fasciculus (ILF) and uncinate fasciculus (UF) among three groups and between SIB and CON. We also proved partly their relationship with the language test as indicated by the significant correlation detected between TLI Impoverished thought/language sub-scale and ILF. We could not find any difference between FEP and CON. These results showed that the abnormalities, especially in the ILF and UF, could be important pathophysiological vulnerability indexes of schizophrenia. Further studies are required to understand better the role of language as a possible endophenotype in schizophrenia with larger samples.