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Yayın Identification of metabolic correlates of mild cognitive impairment in Parkinson's disease using magnetic resonance spectroscopic imaging and machine learning(Springer Science and Business Media Deutschland GmbH, 2022-12) Cengiz, Sevim; Arslan, Dilek Betül; Kıçik, Ani; Erdoğdu, Emel; Yıldırım, Muhammed; Hatay, Gökçe Hale; Tüfekçioğlu, Zeynep; Uluğ, Aziz Müfit; Bilgiç, Başar; Hanagasi, Haşmet; Demiralp, Tamer; Gürvit, Hakan; Öztürk Işıkk, EsinObjective: To investigate metabolic changes of mild cognitive impairment in Parkinson’s disease (PD-MCI) using proton magnetic resonance spectroscopic imaging (1H-MRSI). Methods: Sixteen healthy controls (HC), 26 cognitively normal Parkinson’s disease (PD-CN) patients, and 34 PD-MCI patients were scanned in this prospective study. Neuropsychological tests were performed, and three-dimensional 1H-MRSI was obtained at 3 T. Metabolic parameters and neuropsychological test scores were compared between PD-MCI, PD-CN, and HC. The correlations between neuropsychological test scores and metabolic intensities were also assessed. Supervised machine learning algorithms were applied to classify HC, PD-CN, and PD-MCI groups based on metabolite levels. Results: PD-MCI had a lower corrected total N-acetylaspartate over total creatine ratio (tNAA/tCr) in the right precentral gyrus, corresponding to the sensorimotor network (p = 0.01), and a lower tNAA over myoinositol ratio (tNAA/mI) at a part of the default mode network, corresponding to the retrosplenial cortex (p = 0.04) than PD-CN. The HC and PD-MCI patients were classified with an accuracy of 86.4% (sensitivity = 72.7% and specificity = 81.8%) using bagged trees. Conclusion: 1H-MRSI revealed metabolic changes in the default mode, ventral attention/salience, and sensorimotor networks of PD-MCI patients, which could be summarized mainly as ‘posterior cortical metabolic changes’ related with cognitive dysfunction.Yayın Energy and data cooperation in energy harvesting multiple access channel(IEEE, 2016) Gürakan, Berk; Şişman, Berrak; Kaya, Onur; Ulukuş, SennurWe consider the energy harvesting two user Gaussian multiple access channel (MAC), where both users harvest energy from nature. The users cooperate at the physical layer (data cooperation) by establishing common messages through overheard signals and then cooperatively sending them. In addition, the users cooperate at the battery level (energy cooperation) by wirelessly transferring energy to each other. We find the jointly optimal offline transmit power and rate allocation policy together with the energy transfer policy that maximizes the departure region. We provide necessary conditions for energy transfer, and prove some properties of the optimal transmit policy, thereby shedding some light on the interplay between energy and data cooperation.Yayın Benefiting innovative capabilities of software developer/user communities in developing countries(IEEE, 2010) Ansal, Hacer; Yıldırım, NihanSince technological innovation is generally considered to be a major force in global economic growth, the development of innovative capabilities in developing countries has been a very important policy issue. Free/Libre Open Source Software (FLOSS) has reshaped software technology through the creation of developer/user communities which enabled the collaboration of different parties resulting in the production of Linux and similar software projects. FLOSS user/developer community networks serve not only as "learning, reviewing, and testing" environments for developers, but they may also act as innovation networks that contribute to the improvement of the innovative capabilities of individual developers within the community. Therefore, understanding the characteristics, the motivating factors and the innovative dynamics of these developer communities will provide valuable insight into how to improve the innovative capabilities of developing countries in relation to software.The aim of this paper is to explore the characteristics of FLOSS developer communities in order to discover what benefits they may offer developing countries in generating innovative capabilities related to software. By conducting a survey in the FLOSS user/developer community in Turkey, the demographic characteristics, motivation factors and innovative characteristics of the community are explored and the question of whether these communities may act as innovation networks is examined. It is concluded that FLOSS community networks mostly serve as knowledge sharing and collaboration platforms, however, they do have the potential to evolve into innovation networks if they receive support from the local software industry and academic institutions.Yayın NFC Loyal for enhancing loyalty services through Near Field Communication(Springer US, 2013-02) Özdenizci Köse, Büşra; Ok, Kerem; Coşkun, VedatNear Field Communication (NFC) as an emerging technology is currently leveraged by large standardization efforts and tries to find a suitable ecosystem. NFC enabled mobile devices with integrated smart cards introduce compelling opportunities and new business models. Development of new standards such as secure element (SE), smart card, secure channel, as well as JavaCard enables creating new ecosystems using a concurrent multi application platform which takes advantage of GlobalPlatform standards. We proposed NFC Loyal, which maintains storage, retrieval, and sharing among payment and loyalty applications through our proposed structure, called as Secure Common Domain Management (SCDM) system. SCDM as a centralized database management system on the SE stores valuable information provided by payment applications and shares them with loyalty applications through a secure channel. The direct outcome of using NFC Loyal is the increase in repeat purchases of customers; as well as being a beneficial business plan realized among the payment firms, loyalty firms, and the card owner, resulting in a win-win business model. In this study, we describe NFC Loyal model with its technical infrastructure, and present the NFC Loyal model's life cycle management on SE.Yayın Immitance data modelling via linear interpolation techniques: a classical circuit theory approach(Wiley-Blackwell, 2004-11) Yarman, Bekir Sıddık Binboğa; Kılınç, Ali; Aksen, AhmetWith the advancement of the manufacturing technologies to produce new generation analog/digital communication systems, immitance data modelling has gained renewed importance in the literature. Specifically, models are utilized for behaviour characterization, simulation of physical devices or to design sub-systems with active and passive solid-state devices. Therefore, in this paper, new computer aided tools are presented to model one port immitance data by means of linear interpolation techniques. The basic philosophy of the new modelling tools is based on the numerical decomposition of the immitance data into its minimum and Foster parts. Computer algorithms are presented to model the minimum and the Foster parts of the given immitance data. Implementations of these algorithms are exhibited by means of examples. Depending on the application, modelling tools based on linear interpolation techniques may present 'computational and practical' advantages over the existing interpolation techniques, non-linear curve fittings or regression methods. It is expected that the new modelling tools will be utilized to provide initial circuit topologies to the commercially available analysis/simulation and design packages.Yayın Circuit model for given reflectance data constructed with mixed lumped and distributed elements for high speed/high frequency communication systems(IEEE, 2005) Yarman, Bekir Sıddık Binboğa; Şengül, Metin; Kılınç, Ali; Aksen, AhmetIn this paper, a reflectance-based "non linear interpolation method" is presented to model the measured or computed data, obtained from a "passive one-port physical device" using mixed lumped and distributed elements. Mixed element model is constructed with cascade connection of series inductors [L], commensurate transmission lines or so called Unit Elements [UE] and shunt capacitors[C]. Basis of the new model rests on the numerical generation of the scattering parameters of the lossless two-port constructed with cascade connection of simple [L]-[UE]-[C] elements which describes a lossless 2-port in Darlington sense. The new modeling technique does not require direct optimization of the circuit elements of the selected topology. Rather, two-variable reflection coefficient is directly determined by means of a non linear but "convergence guaranteed" interpolation process to best fit the given data. A low-pass filter input reflection coefficient modeling example is included to exhibit the utilization of the proposed modeling method.Yayın Energy and data cooperative multiple access channel with intermittent data arrivals(IEEE, 2018-03) Gürakan, Berk; Kaya, Onur; Ulukuş, ŞennurWe consider an energy harvesting two user cooperative Gaussian multiple access channel, where both of the users harvest energy from nature. The users cooperate at the physical layer (data cooperation) by establishing common messages through overheard signals and then cooperatively sending them. We study two scenarios within this model. In the first scenario, the data packets arrive intermittently over time. We find the optimal offline transmit power and rate allocation policy that maximize the departure region. We first show that there exists an optimal policy, in which the single user rate constraints in each time slot are tight, yielding a one-to-one relation between the powers and rates. Then, we formulate the departure region maximization problem as a weighted sum departure maximization in terms of rates only. Next, we propose a sequential convex approximation method to approximate the problem at each step and show that it converges to the optimal solution. We solve the approximate problems using an inner-outer decomposition method. In the second scenario, the data packets are available at the beginning of the transmission, but the users now have the ability to cooperate at the battery level (energy cooperation), in addition to data cooperation. The energy cooperation is facilitated by wireless energy transfer and is bidirectional. For this scenario, we find the jointly optimal offline transmit power and rate allocation policy together with the energy transfer policy that maximize the departure region. We provide necessary conditions for energy transfer and prove some properties of the optimal transmit policy, thereby shedding some light on the interplay between energy and data cooperation.Yayın Force-directed approaches to sensor localization(SIAM, 2006) Efrat, Alon; Forrester, David; Iyer, Anand; Kobourov, Stephen G.; Erten, CesimWe consider the centralized, anchor-free sensor localization problem. We consider the case where the sensor network reports range information and the case where in addition to the range, we also have angular information about the relative order of each sensor's neighbors. We experimented with classic and new force-directed techniques. The classic techniques work well for small networks with nodes distributed in simple regions. However, these techniques do not scale well with network size and yield poor results with noisy data. We describe a new force-directed technique, based on a multi-scale dead-reckoning, that scales well for large networks, is resilient under range errors, and can reconstruct complex underlying regions.Yayın Lossless matched broadband power amplifiers(CRC Press Taylor & Francis Group, 2016) Grebennikov, Andrei; Kumar, Narendra; Yarman, Bekir Sıddık Binboğa[No abstract available]Yayın Channel adaptive encoding and decoding strategies and rate regions for the three user cooperative multiple access channel(IEEE, 2008) Edemen, Çağatay; Kaya, OnurFor a cooperative Gaussian multiple access channel (MAC), we propose a new channel adaptive three user cooperation strategy, based on a non-trivial extension of block Markov super-position encoding. We obtain the expressions for the resulting achievable rate region. We demonstrate through simulations that the participation of an extra user in cooperation provides significant rate improvements. The proposed strategy also improves upon our earlier results on the three user cooperative MAC [1], under certain channel conditions.
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