Makale Koleksiyonu | Psikoloji Bölümü

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https://hdl.handle.net/11729/4894

Listeleniyor 1 - 20 / 201

The mediating effect of self compassion in the relationship between job stress and burnout levels among employees
(SAGE Publications Inc., 2026-02-13) Günay, Ezgi; Ünver, Buket; Yılmaz, Simay
Objective: This study investigates the role of self-compassion as a mediator in the relationship between job stress and burnout among employees. While job stress is widely recognized as a critical factor leading to burnout, it has been suggested that self-compassion may be associated with a reduction in these negative effects. Method: Participants were 429 actively employed adults living in Turkey (50.6% female). The data were gathered using an online administration of standardized psychological scales, that is, Job Stressor Appraisal Scale, Copenhagen Burnout Scale, and Self-Compassion Scale. Four dimensions of work stress “Role and Workload, Role Inadequacy, Organizational Rules & Practices, and Subordinate Relations” are taken into consideration in the volumetric model. Path analysis with bootstrapping (5,000 resamples) was implemented using Mplus statistical software, with gender, economic condition, and way of working during COVID-19 as covariates. Findings: The model fit was acceptable in path analysis. Role and workload and role inadequacy had a significant direct impact on burnout. Self-compassion had a significant mediating impact on the relationship between role and workload and burnout and the relationship between role inadequacy and burnout. Conversely, for organizational rules and practices and subordinate relations, both direct and mediating effects were non-significant. The model accounted for 21% and 52% for variance in self-compassion and burnout, respectively. Conclusion: This study emphasises the mediating role of self-compassion in the effect of job stressors on burnout. These findings suggest that interventions promoting self-compassion in the workplace may be effective in reducing employee burnout.
Validation and normative data study for the Turkish version of the movie for the assessment of social cognition (MASC-TR)
(Oxford University Press, 2026-02-05) Şandor, Serra; Hıdıroğlu-Ongun, Ceren; Tanfer, Mehmet Can; Gürkaş, Sena; Bora, Emre; Yıldırım, Elif
Objective This study aimed to adapt the Movie for the Assessment of Social Cognition (MASC) into Turkish (MASC-TR), examine its psychometric properties, and establish normative data. Additionally, the study investigated the discriminative validity of the MASC-TR in differentiating individuals with autism spectrum disorder (ASD) from healthy controls. Methods The sample comprised 228 healthy adults and 29 individuals with ASD aged 18–45 years. Participants completed the MASC-TR along with established measures of theory of mind (ToM)—the Reading the Mind in the Eyes Test (RMET) and the Faux Pas Recognition Test (FPRT)—as well as non-social cognitive tasks assessing attention, working memory, and executive functions. Reliability analyses included internal consistency and test–retest reliability. Construct validity was assessed via convergent and discriminant correlations. Group comparisons and receiver operating characteristic analyses were used to evaluate discriminative validity, while multifactorial analysis of variance and regression analyses examined demographic effects. Results The MASC-TR demonstrated acceptable internal consistency (α=0.75) and excellent test–retest reliability (ICC=0.98). Significant positive correlations with RMET and FPRT supported convergent validity. Education level emerged as the only significant demographic predictor of MASC-TR performance. The MASC-TR successfully differentiated individuals with ASD from controls (t=−3.87, p<.001), with an optimal cutoff of 23.5 yielding 97% sensitivity and 52% specificity (area under the curve=0.72). Conclusions The findings indicate that the MASC-TR is a valid and reliable measure of social cognition in Turkish adults. The availability of culturally adapted normative data enhances its clinical and research utility for assessing ToM functioning across populations.
Bipolar bozuklukta çalışma statüsü ve ilaç uyumu: "kuram temelli bir değerlendirme"
(İstanbul Bilgi Üniversitesi, 2021-10-04) Ünver, Buket; Berk, Özlem Sertel; Karamustafalıoğlu, Nesrin
Bu çalışmanın amacı ilaç uyumunun farklı çalışma statüsüne sahip bipolar bozukluk tanılı hastalarda nasıl farklılaştığını sağlık davranış modellerinden biri olan Bütünleşik Davranış Modeli (BDM) perspektifinden incelemek ve çalışma statüsünün hastalık şiddeti ve sosyodemografik değişkenlerle olan ilişkisini değerlendirmektir. Bu amaç doğrultusunda 167 bipolar bozukluk tanılı hastaya ulaşılmıştır. Veri toplama araçları olarak BDM Bipolar Bozukluk İlaç Uyumu Bataryası, Tıbbi Tedaviye Uyum Oranı Ölçeği ve İlaç Uyumunu Bildirim Ölçeği, kanda ölçülen ilaç düzeyi açısından ilaç uyumu kullanılmıştır. Yapılan analizler sonucunda memurların diğer çalışma statüsüne sahip gruplara göre hem hastalık şiddetinin hem de ilaç uyumsuzluğunun daha yüksek olduğu saptanmıştır. Özellikle bipolar bozukluk tanılı memur gruplarında ilaç uyumuna yönelik müdahale programlarına ihtiyaç duyulduğu düşünülmektedir.
Beyaz yakalı çalışanlarda mükemmeliyetçilik ve tükenmişlik arasındaki ilişkide psikolojik dayanıklılığın aracı rolü
(Institute of Economic Development and Social Research, 2023-06-20) Erbay Erşen, Merve; Akçınar, Berna
Bu araştırmanın amacı, beyaz yaka çalışanlarda mükemmeliyetçi özellikler ile tükenmişlik arasındaki ilişki ve bu ilişkide psikolojik dayanıklılığın aracı rolünü incelemektir. Bu doğrultuda üretim planlama, üretim yönetimi, kalite yönetimi vekontrol, iç denetim, Ar-Ge, bakım onarım, pazarlama gibi alanlarda çalışan kişilere bir çevrim içi anket platformu olan Google Forms aracılığı ile ölçekler ulaştırılmış ve çalışmanın verileri toplanmıştır. Araştırmada Sosyodemografik Özellikler ve Veri Formu, Conor-Davidson Psikolojik Sağlamlık Ölçeği, Çok Boyutlu Mükemmeliyetçilik Ölçeği ve Maslach Tükenmişlik Ölçeği kullanılmıştır. Verilerin analizi için betimleyici istatistikler, Pearson korelasyon analizi ve bir grup tekli ve çoklu regresyon analizi uygulanmıştır. Bu analizlerden elde edilen bulgulara göre, ailesel beklentiler alt boyutu hariç, uyumsuz mükemmeliyetçilik alt boyutları ile tükenmişliğin her iki alt boyutu (duyarsızlaşma ve duygusal tükenme) arasında pozitif yönde korelasyon ilişkisi olduğu görülmektedir. Uyumlu mükemmeliyetçilik alt boyutlarından düzen, duygusal tükenme ile negatif yönde, kişisel standartlar alt boyutu ise duyarsızlaşma ile pozitif yönde korelasyon ilişkisine sahiptir. Ayrıca, bulgular psikolojik dayanıklılığın, uyumsuz mükemmeliyetçilik ve tükenmişlik arasındaki ilişkide kısmi aracılık etkisini ortaya koymaktadır. Sonuçlar değerlendirildiğinde, mükemmeliyetçi özelliklerin uyumlu ve uyumsuz mükemmeliyetçilik olmak üzere iki boyutta ele alınmasının, tükenmişlik kavramını anlamada daha detaylı veri sağlayacağı ve psikolojik dayanıklılık gibi tükenmişliğe tampon etkisi yaratabilecek kavramların ele alınmasının önemli olduğu düşünülmektedir.
Formal thought disorder and familial risk in first-episode psychosis: A study of cortical thickness and neuroimaging-transcriptomic association analysis
(Elsevier Ireland Ltd, 2026-01-16) Çabuk, Tuğçe; Zhang, Yuanchao; Palaniyappan, Lena; Şahin Çevik, Didenur; Avcı, Hanife; Çakmak, Işık Batuhan; Yılmaz Kafalı, Helin; Şenol, Bedirhan; Karlı Oğuz, Kader; Toulopoulou, Timothea
Formal thought disorder (FTD), a prominent feature of schizophrenia, encompasses disruptions in thought, language, and communication. This study examines cortical thickness (CT) alterations in first-episode psychosis (FEP) patients (N = 24), their siblings (SIB) (N = 21), and healthy controls (CON) (N = 21) to explore potential neural correlates of FTD. Using structural MRI, we analyzed whole-brain CT and its relationship with positive and negative FTD measured by Thought and Language Index. Out-of-sample spatial correlations of gene expression with regional CT were also performed using a transcriptomic dataset. FEP had significant CT reductions in right middle frontal gyrus (MFG) compared with SIB and CON and in superior frontal gyrus (SFG) compared to CON; but SIB did not differ from CON. GLM analyses demonstrated that negative FTD exerted a significant main effect on CT in the MFG and SFG. By contrast, positive FTD showed no significant associations with CT. Neuroimaging-transcriptomic association analysis identified key biological pathways linked to cortical morphology. These findings emphasize the specific association between negative FTD and CT alterations in frontal brain regions, confirming prior reports. Future research should examine larger cohorts and investigate additional FTD subtypes to further elucidate neural correlates and potential familial risks of schizophrenia.
Kekemeliği olan ve olmayan yetişkin bireylerin psikolojik dayanıklılıkları üzerinde duygu düzenleme güçlüğünün etkisi
(Yeditepe Üniversitesi, 2023-12-28) Özkan, Nilüfer; Akçınar, Berna
Bu araştırmada kekemeliği olan ve olmayan yetişkin bireylerin psikolojik dayanıklılıkları üzerinde duygu düzenleme güçlüğünün yordayıcı etkisi incelenmiştir. Kekemeliği olan ve olmayan yetişkin bireylerin psikolojik dayanıklılıkları kıyaslanarak, sosyodemografik özelliklerin psikolojik dayanıklılık üzerindeki etkisi incelenmiş ve kekemeliği olan örneklem grubunun belli özellikleri tespit edilmiştir. Araştırmanın katılımcılarını, 83 kekemeliği olan 139 kekemeliği olmayan toplam 222 yetişkin oluşturmaktadır. Ölçüm aracı olarak Kişisel Bilgi Formu, Duygu Düzenleme Güçlüğü Ölçeği (DDGÖ) ve Yetişkinler İçin Psikolojik Dayanıklılık Ölçeği (YPDÖ) kullanılmıştır. Araştırma sonucunda, kekemeliği olan yetişkinlerle kekemeliği olmayan yetişkinler arasında psikolojik dayanıklılık toplam puanları arasında istatistiksel açıdan anlamlı bir fark olduğu tespit edilmiştir. Kekemeliği olan yetişkinlerin psikolojik dayanıklılıkları daha düşük bulunmuştur. Bunun yanı sıra, duygu düzenleme güçlüğü ile psikolojik dayanıklılık arasında negatif yönde güçlü bir ilişkinin olduğu tespit edilmiş ve kekemeliği olan ve olmayan bireylerde duygu düzenleme güçlüğünün, psikolojik dayanıklılığı anlamlı şekilde yordadığı görülmüştür. Bu araştırma, elde edilen sonuçlar doğrultusunda duygu düzenlemenin psikolojik dayanıklılık üzerinde ne kadar kritik bir rol oynadığını göstermektedir. Bu bulgular, kekemeliği olan bireylerin kekemelik deneyimini şekillendirmek veya kontrol altına almak, ayrıca bu bireylerin yaşam kalitesini artırmak için daha etkili terapötik yaklaşımların geliştirilmesinde önemli bir yol gösterici olabileceği düşünülmektedir.
Effects of transcranial direct current stimulation on inhibition-related oscillatory brain activity during an emotional antisaccade task
(Kare Publishing, 2025-12) Sütçübaşı, Bernis; Küçük, Zeynep; Tarman, Güliz Zeynep; Metin, Barış; Sarı, Berna
Objective: Previous studies have shown that transcranial direct current stimulation (tDCS) applied to the dorsolateral prefrontal cortex (dlPFC) can enhance attentional performance and influence emotional processing. However, the neural mechanisms underlying these effects are not fully understood. This study aimed to investigate oscillatory changes following tDCS over the dlPFC, with the hypothesis that anodal stimulation of the right dlPFC would modulate inhibition-related oscillations in the presence of threatening faces compared with left dlPFC stimulation. Method: Thirty-six healthy participants underwent bilateral tDCS to the dlPFC. One group received anodal tDCS to the right dlPFC and cathodal to the left dlPFC, while the second group received the opposite montage. A control group received sham stimulation. Before and after stimulation, behavioral performance and event-related theta oscillations were recorded during an antisaccade task involving neutral and angry faces. Results: Compared to the left-dlPFC group, the right-dlPFC group showed lower theta responses at F3 after anodal stimulation, particularly during antisaccade trials with angry faces, which are known to impose higher inhibitory demands due to threat salience. No group differences were found in saccade latencies. These findings suggest that anodal right dlPFC stimulation modulates oscillatory activity related to inhibitory control under emotionally salient conditions. Conclusion: A decrease in theta oscillations following anodal tDCS over the right dlPFC may indicate enhanced inhibitory control during the processing of threatening stimuli. These results point to a potential role of dlPFC-targeted tDCS in regulating cognitive control and emotional processing, particularly in individuals with difficulties in these domains. However, the directionality and causality of these effects cannot be conclusively established due to limitations of the current study design.
Effect of modulated anodal stimulation over the dorsolateral prefrontal cortex on working memory: a preliminary study
(Istanbul University, 2025-12-31) Küçük, Zeynep; Erdoğan, Ezgi Tuna; Kurt, Adnan; Karamürsel, Sacit
Objectives: Working memory has two components: temporary storage and manipulation of the information necessary for cognitive behavior through the central executive system. This study aimed to investigate the effects of modulated anodal transcranial direct current stimulation (mtDCS) of the dorsolateral prefrontal cortex on working memory. Materials and Methods: Twelve volunteers without neurological or psychiatric disorders and without drug use participated. Working memory performance was assessed with a visual 3-back task using consonant letters during stimulation. A 20/minute training session was conducted to facilitate learning, and participants who achieved an accuracy rate of 50% or higher proceeded to the main experiment. Four stimulation conditions were applied, each lasting 10 minutes: mtDCS-11 Hz and mtDCS-22 Hz (1.70 mA offset, 0.35 mA peak/to/peak), direct current (DC) (2 mA), and sham. Reaction times and total correct responses were recorded. Results: Statistical analysis of the left dorsolateral prefrontal cortex (DLPFC) stimulation revealed a significant difference in the mean numbers of correct responses among the mtDCS and transcranial direct current stimulation (tDCS) conditions, but not compared with sham. The mean number of correct responses under mtDCS-11Hz and mtDCS-22Hz was significantly lower than under DC stimulation; however the performance decrement under 11 Hz mtDCS was the most pronounced among the active conditions. Conclusion: mtDCS-11Hz and mtDCS-22Hz negated the subtle facilitation of tDCS might have provided.
Ebeveyn tutumları ve çocuk davranış problemleri arasındaki ilişkide ebeveyn mükemmeliyetçiliğinin aracı rolü
(Galenos Publishing House, 2025-11-11) İnce, Merve; Akçınar, Berna; Yılmaz, Simay
Amaç: Bu çalışma, annelerin mükemmeliyetçiliğinin, annelerin ebeveynlik stilleri ile çocukların içselleştirme ve dışsallaştırma davranış problemleri arasındaki ilişkide aracılık rolünü incelemeyi amaçlamaktadır. Gereç ve Yöntem: Örneklem, 3-6 yaş arası çocukları olan 271 anneden oluşmaktadır. Katılımcılardan sosyodemografik bilgi formu, Ebeveyn Tutum Ölçeği, Hacettepe Ruhsal Uyum Ölçeği ve Çok Boyutlu Mükemmeliyetçilik Ölçeğini doldurmaları istenmiş ve veriler çevrimiçi olarak toplanmıştır. Bulgular: Çalışmanın ana hipotezini test etmek için yapılan analiz bulgularına göre demokratik ebeveynlik, içselleştirme (b=-0,117, p<0,05) ve dışsallaştırma (b=-0,076, p<0,05) davranış problemlerini negatif yönde yordamıştır. Bu ilişkilerde annenin kendine yönelik mükemmeliyetçiliği (KYM) ve sosyal olarak belirlenen mükemmeliyetçilik (SBM) aracılık etmemiştir. Otoriter ebeveynlik, içselleştirme (b=0,046, p<0,05) ve dışsallaştırma (b=0,049, p<0,05) davranış problemleriyle pozitif yönde ilişkilendirilmiş ve bu problemler üzerindeki etkilerinde KYM ve SBM aracılık rolü üstlenmemiştir. Buna karşın, aşırı korumacı ve izin verici tutumlar bu davranış problemlerini anlamlı bir şekilde yordamamıştır. Ayrıca, annelerin KYM’nin, aşırı korumacı ve izin verici ebeveynlik tutumları ile içselleştirme ve dışsallaştırma davranış problemleri arasındaki ilişkide aracılık etkisi olmadığı bulunmuş; ancak SBM’nin aşırı koruyucu ebeveyn tutumu ile içselleştirme [b=0,017, standart hata (SH)=0,009, güven aralığı (GA): (0,003, 0,038)] ve dışsallaştırma [b=0,012, SH=0,007, GA: (0,001, 0,029)] davranış problemlerinde ve izin verici ebeveyn tutumu ile içselleştirme davranış problemi [b=0,013, SH=0,008, GA: (0,000, 0,033)] arasında aracılık etkisinde bulunduğu görülmüştür. Sonuç: Bu çalışma, ebeveynlik tutumları ve özelliklerinin çocukların ruh sağlığı üzerindeki önemli rolünü vurgulamakta, ebeveynlerin etkili ve olumlu ebeveynlik yaklaşımlarını benimsemeleri için pratik müdahalelerin gerekliliğini belirtmektedir.
Healing through art: a systematic review and meta-analysis of art therapy in children and adolescents with chronic illnesses
(Taylor and Francis Ltd., 2025-11) Yıldız, Ecemnur; Akçinar, Berna; İnci Namlı, Nur
Children and adolescents with chronic illnesses face elevated risks of psychological difficulties, including anxiety and reduced quality of life (QoL). Art therapy (AT) has emerged as a promising intervention. This study systematically reviews and analyzes the effectiveness of AT in improving QoL, anxiety, and pain in this population. A comprehensive search identified a total of 12 randomized controlled trials from 2000 to 2024, including 408 participants aged 0–18. Data were analyzed using Hedges’ g and a random-effects model. Quality assessments followed the Cochrane Risk of Bias 2 (RoB2) tool. Subgroup analyses explored potential moderators. QoL was analyzed separately by child and parent reports. AT showed a moderate, significant effect on child-reported QoL (Hedges’ g =.40, 95% CI [0.27; 0.53], p =.001) but a non-significant effect in parent reports (Hedges’ g =.43, 95% CI [−.03; 1.20], p =.21). A significant large effect was found for pain reduction (Hedges’ g = –.63, 95% CI [−1.19; −0.07], p =.03). For anxiety, AT had a large but non-significant effect (Hedges’ g = –.71, 95% CI [−2.24; 0.82], p =.23). Heterogeneity was substantial, but no significant publication bias was detected. AT appears promising for enhancing QoL, reducing pain in children with chronic illnesses. Further studies are needed to strengthen evidence and clarify clinical applications.
Efficacy, all-cause discontinuation, and safety of serotonergic psychedelics and MDMA to treat mental disorders: a living systematic review with meta-analysis
(Elsevier B.V., 2025-12) Højlund, Mikkel; Yılmaz Kafalı, Helin; Kırmızı, Begüm; Fusar-Poli, Paolo; Correll, Christoph U.; Cortese, Samuele; Sabé, Michel; Fiedorowicz, Jess; Saraf, Gayatri; Zein, Josephine; Berk, Michael; Husain, Muhammad I.; Rosenblat, Joshua D.; Rubaiyat, Ruby; Corace, Kim; Wong, Stanley; Hatcher, Simon; Kaluzienski, Mark; Yatham, Lakshmi N.; Cipriani, Andrea; Gosling, Corentin J.; Carhart-Harris, Robin; Tanuseputro, Peter; Myran, Daniel T.; Fabiano, Nicholas; Moher, David; Mayo, Leah M.; Nicholls, Stuart G.; White, Tracy; Prisco, Michele De; Radua, Joaquim; Vieta, Eduard; Ladha, Karim S.; Katz, Jay; Veroniki, Areti A.; Solmi, Marco
Serotonergic psychedelics and 3,4-methylendioxtmethamphetamine (MDMA) are promising treatments for mental disorders with a continuously evolving evidence base. We searched Pubmed/Scopus/clinical trial registries up to 08july2025 for double-blind randomized controlled trials (RCTs) testing MDMA or serotonergic psychedelics in patients with mental disorders. Primary outcomes were change in disease-specific symptoms and all-cause discontinuation. Standardized mean differences (SMD) and relative risk (RR) were estimated using random-effects meta-analysis. Risk of bias (RoB) was assessed with Cochrane’s RoB-tool version 2 and certainty of evidence with GRADE. The review is maintained as living systematic review ( https://ebipsyche-database.org/ ). We included 30 RCTs (1480 participants; female=45.8 %; with psychological support=83.3 %; high RoB=83.3 %). In post-traumatic stress disorder (PTSD), MDMA reduced PTSD symptoms compared to any control ( k = 11; SMD=-0.85 [-1.09; -0.60]; I2=0 %; GRADE=low). In major depressive disorder (MDD), psilocybin/ayahuasca/LSD reduced depressive symptoms ( k = 8; SMD=-0.62 [-0.97; -0.28]; I2=55 %; GRADE=very low). In anxiety disorders, both MDMA and serotonergic psychedelics reduced anxiety symptoms (SMDMDMA=-1.18 [-2.04; -0.32]; I2=0 %; k = 2; GRADE=low and SMDserotonergic=-0.88 [-1.70; -0.06]; I2=54 %; k = 5; GRADE=very low). In alcohol use disorder, neither psilocybin nor LSD reduced abstinence rates ( k = 6; RR=1.42 [0.89; 2.26]; I2=7 %; GRADE=very low). In attention-deficit hyperactivity disorder (ADHD), LSD did not reduce ADHD symptoms ( k = 1; SMD=0.22 [-0.32; 0.76]; GRADE=very low). Moderate certainty in evidence was only found for MDMA on PTSD symptoms when compared to placebo. MDMA/serotonergic psychedelics were not associated with higher risk of all-cause discontinuation (RRMDMA=0.74 [0.32; 1.72]; RRserotonergic=0.81 [0.56; 1.15]). Overall, MDMA/serotonergic psychedelics are promising for the treatment of PTSD, MDD, and anxiety disorders with moderate to large effect sizes. Pragmatic trials, long-term, head-to-head trials exploring the role of psychological support, aiming to identify predictors of response, and accounting for expectancy and functional unblinding are needed. Studies addressing these limitations will likely be required for regulatory approval of psychedelic drugs.
Differential associations between mentalizing dimensions and psychopathy subtypes: the moderating role of borderline personality traits
(Frontiers Media SA, 2025-10-15) Ünver, Buket
Introduction Psychopathy comprises primary and secondary subtypes with distinct affective-interpersonal profiles. Mentalizing, i.e., the capacity to understand one's own and others' mental states, may help explain this heterogeneity. This study tested how three mentalizing dimensions (Self-Related, Other-Related, and Motivation to Mentalize) relate to psychopathy subtypes and whether borderline personality traits (BPTs) moderate these associations.Methods Adults from a community sample (N = 953) completed validated measures of psychopathy, mentalizing, and BPTs. BPTs were modeled as a continuous variable. Multivariable linear regressions predicted primary and secondary psychopathy from the three mentalizing facets while adjusting for age, gender, socioeconomic status, and psychiatric diagnosis. Moderation was examined via interaction terms between each mentalizing facet and BPTs; significant interactions were probed at -1/0/+1 SD of BPT scores.Results Higher Motivation to Mentalize and greater Self-Related Mentalizing were uniquely associated with lower primary psychopathy; Other-Related Mentalizing was not a unique predictor. For secondary psychopathy, Self-Related Mentalizing and, to a lesser extent, Motivation to Mentalize were inversely associated; Other-Related Mentalizing was not significant. BPTs significantly moderated only the association between Motivation to Mentalize and primary psychopathy (stronger inverse association at higher BPTs); no moderation effects emerged for secondary psychopathy.Conclusion Findings indicate that motivation and self-related aspects of mentalizing are protective correlates of psychopathic traits, with moderation by BPTs limited to primary psychopathy. Targeting motivation to consider mental states and strengthening self-reflective capacity may enhance psychological intervention strategies, particularly for individuals high in primary psychopathy with elevated borderline features.
Selective influence of dopamine on electrocortical signatures of error monitoring: a combined EEG and immersive virtual reality study in Parkinson's disease
(Cold Spring Harbor Lab Press, 2022-04-14) Pezzetta, Rachele; Özkan, Duru Gün; Era, Vanessa; Tieri, Gaetano; Zabberoni, S.; Taglieri, Sara; Costa, A.; Peppe, Antonella; Caltagirone, Carmen; Aglioti, Salvatore Maria
Detecting errors in ones own and others actions is likely linked to the discrepancy between intended or expected and produced or observed output. To detect and process the occurrence of salient events seems associated to the release of dopamine, the balance of which is profoundly altered in Parkinsons disease (PD). EEG studies in healthy participants indicate that the occurrence of errors in observed actions triggers a variety of electrocortical indices (like mid-frontal theta activity, error-related delta and the Error Positivity, oPe), that seem to map different aspects of error detection and performance monitoring. Whether these indices are differently modulated by dopamine in the same individual has never been investigated. To explore this issue, we recorded EEG markers of error detection by asking healthy controls (HCs) and PD patients to observe ecological reach-to-grasp a glass actions performed by a virtual arm seen in first person perspective. PD patients were tested under their dopaminergic medication ( on-condition), and after dopaminergic withdrawal ( off-condition). HCs showed a clear oPe and an increase of delta and theta power during the observation of erroneous vs. correct actions. In PD patients, oPe and delta responses were always preserved. Crucially, however, an error-related increase of theta power was found in on but not in off state PD patients. Thus, different EEG error signatures may index the activity of independent systems and error related theta power is selectively modulated by dopamine depletion. Our findings may pave the way to the discovery of dopamine-related biomarkers of higher-order motor cognition dysfunctions that may have crucial theoretical and clinical implications. Significance StatementDopaminergic neurons respond to salient events during performance monitoring. Yet, the impact of dopamine depletion on the human reactivity to observed errors is still unclear. We recorded EEG in patients with Parkinsons Disease (PD) under dopaminergic treatment ( on-condition) and medication withdrawal ( off-condition) while they observed correct and erroneous goal-related actions performed by a virtual limb. Analysis of Error Positivity (oPe) and theta and delta power increase, markers of physiological error-monitoring, indicates that while the formers were intact, the latter was preserved in the on and altered in the off condition. Thus, different EEG markers of error monitoring likely rely on independent circuits. Moreover, mid-frontal theta activity alterations may represent a marker of dopamine-related neurophysiological impairments of higher-order cognition.
Farklı rollerde ebeveynleşme ve benlik ayrışması arasındaki ilişkide algılanan yararın aracı rolü
(Klinik Psikoloji Araştırmaları Derneği, 2025-08-25) Ünver, Buket
Bu araştırmanın amacı, farklı rollerde ebeveynleşme ve benliğin ayrışması arasındaki ilişkide algılanan yararın aracı rolünün incelenmesidir. Kurulan model, ebeveyn odaklı ve kardeş odaklı ebeveynleşme olmak üzere iki ayrı modelde test edilmektedir. Çalışmanın örneklemi 18-25 yaş arası, 137 kadın (%54.8) ve 113 erkek (%45.2) olmak üzere toplam 250 kişiden oluşmaktadır. Katılımcılara Demografik Bilgi Formu, Ebeveynleşme Envanteri ve Benliğin Ayrımlaşması Ölçeği sunulmuştur. Verilerin analizinde bağımsız gruplar t-testi, Pearson korelasyon analizi ve aracı etki analizi kullanılmıştır. Elde edilen bulgulara göre kadınlarda benlik ayrışmasının erkeklere göre daha düşük olduğu görülmüştür. Aracı etki analizinde cinsiyet kontrol değişkeni olarak ele alınmış ve ebeveynleşme ile benliğin ayrışması arasında ebeveynleşmeden algılanan yararın aracı rolü bulunmuştur. Bireyin her iki rol için de ebeveynleşme yaşantısı arttıkça bu yaşantıdan algıladığı yarar azalmakta ve algılanan yarar azaldıkça da bireyin benlik ayrışma düzeyinin azaldığı görülmektedir. Bu doğrultuda, ebeveynleşme deneyimleyen kişinin benlik ayrışmasına ilişkin zorlukları erken dönem yaşantılarını yorumlama biçimleriyle ilişkili olabileceği görülmektedir. Özellikle ebeveynleşme deneyimine dair olumlu tutumlar, bireyin ayrışma sürecine katkı sağlayabilir.
Algılanan ebeveyn reddi ve borderline kişilik inançları arasındaki ilişkide reddedilme duyarlılığı ve öfkenin aracı rolü: cinsiyet temelli sıralı aracı etki modeli
(İstanbul University Press, 2025-07-29) Önürme, Güneş Beyza; Akyunus, Miray; Ünver, Buket
Bilişsel kurama göre borderline kişilik bozuklukluğu, kökeni çocukluk çağı deneyimlerine dayanan kendine özgü işlevsiz inançlar ile karakterizedir. Çaresizlik, güvensizlik ve terkedilme korkusunu merkezine alan bu inançlar, yoğun öfke tepkileri ve davranışlarda aşırılıklar gibi belirtilere neden olmaktadır. Çocuklukta ebeveynden algılanan red, ilerleyen yıllarda reddedilme duyarlılığının gelişmesine, bu duyarlılık ise kişiler arası ilişkilerde algılanan red deneyimlerinde artışa yol açabilmektedir. Tekrarlayan reddedilme algısı hayal kırıklığı, acı ve öfke gibi tepkileri şiddetlendirebilir. Yıkıcı duygusal ve davranışsal tepkilerin ilişkilere verdiği zarar ise mevcut işlevsiz inançları pekiştirmektedir. Bu çalışmanın amacı, çocuklukta algılanan ebeveyn reddi ile borderline kişilik bozukluğu inançları arasındaki ilişkide reddedilme duyarlılığı ve sürekli öfkenin sıralı aracı etkisinin sınanmasıdır. Araştırma Türkiye toplumu örnekleminden 18-72 yaş arası 550 katılımcı ile yürütülmüştür. Sosyodemografik ve Kişisel Bilgi Formu, Yetişkin Ebeveyn Kabul-Red Ölçeği/Kısa Form, Yetişkin Reddedilme Duyarlılığı Ölçeği, Sürekli Öfke ve Öfke İfade Tarzı Ölçeği-Sürekli Öfke alt ölçeği ve Kişilik İnanç Ölçeği/Kısa Formu-Borderline Kişilik Bozukluğu alt ölçeği aracılığıyla çevrimiçi veri toplanmıştır. Araştırma bulguları hem anneden hem de babadan algılanan reddin, reddedilme duyarlılığı ve sürekli öfkenin sıralı aracılığıyla borderline kişilik bozukluğu inançlarını yordadığını göstermiştir. Ayrıca kadınlarda hem anneden hem de babadan algılanan reddin önce reddedilme duyarlılığını, ardından sürekli öfkeyi artırarak, borderline kişilik bozukluğu işlevsiz inançlarının gelişiminde rol oynadığını ortaya koymuştur. Erkeklerde ise, algılanan anne ve baba reddinin, reddedilme duyarlılığı ve borderline kişilik bozukluğu inançları ile anlamlı düzeyde ilişkili olduğu, ancak mevcut çalışmada önerilen sıralı aracı etki mekanizmasının yordayıcı gücünün olmadığı görülmüştür. Bu çalışma borderline kişilik özelliklerinin ve bilişsel işleyişinin cinsiyet temelli farklılıklarının anlaşılmasına katkı sağlamaktadır. Bulgular, kadınlarda işleyen mekanizmayı açıklamakla birlikte, erkeklerde alternatif modellerin test edilmesinin gerekliliğini ortaya koymaktadır.
The mediating role of schema modes in the relationship between parentification and codependency
(SAGE Publications Inc., 2025-07) Ünver, Buket; Önürme, Güneş Beyza
The aim of this study is to examine the mediating role of schema modes between parentification in different roles and codependency. The sample of the study consists of 599 Turkish women aged between 18 and 64. Firstly, Pearson correlation analysis was conducted, revealing that most of the variables were significantly correlated. Secondly, mediating analysis was performed. The results showed that vulnerable child, angry child, compliant surrender, and demanding parent modes mediated the relationship between parent-focused parentification and codependency. The relationship between sibling-focused parentification and codependency was found to be mediated by the happy child, punitive parent, and demanding parent mode. These findings indicate that parentification in different roles are associated with codependency in women through distinct schema modes, with the exception of the demanding parent mode, which appeared in both paths. Furthermore, the results highlight that disruptions in the hierarchical structure of the early parent-child relationship shapes emotional and cognitive structures in adulthood, potentially contributing to the development of dysfunctional relationship dynamics.
Understanding the development of eye movement desensitization and reprocessing therapy for children: findings from a bibliometric study
(Springer Publishing Co., 2025-05-20) Çitil Akyol, Canan; İnci İzmir, Sevim Berrin
Bibliometric analysis is a quantitative method used to determine the development of a specific academic field, publication trends, the most influential authors, and key topics. Systematically analyzing research on the use of eye movement desensitization and reprocessing (EMDR) in children and adolescents is important for identifying the prominent themes in this area and revealing future research needs. Therefore, this study aims to systematically examine the academic development in this field by taking a bibliometric perspective on the existing literature regarding EMDR applications in children and adolescents. This study examines academic works in the fields of EMDR and child-adolescent mental health conducted between 1998 and 2024 by scanning for the keywords "EMDR", "children", and "child" using a bibliometric analysis approach. A total of 358 papers were found in the Scopus database and published between 1998 and early 2024, and only 223 of them were included in the analysis. The most cited authors, journals, organizations, countries, citation trends, key topics, and current growth were analyzed. The findings indicate that EMDR and child research are experiencing robust scientific growth and are receiving increasingly broader academic and clinical attention.
Therapist's assessment of their patient's session-level emotional processes: validation of the in-session patient affective reactions questionnaire–clinician form
(John Wiley and Sons Inc, 2025-08-06) Stefana, Alberto; Ünver, Buket; Vieta, Eduard; Fusar-Poli, Paolo; Youngstrom, Eric Arden
Background: The current study aimed to evaluate a therapist version of the in‐Session Patient Affective Reactions Questionnaire(SPARQ). The SPARQ was developed to assess a pattern of emotions, thoughts, and behaviors experienced by a patient towardtheir therapist during a session. The SPARQ has existed only as a patient self‐report measure and has demonstrated promise as apsychotherapy process measure. This study intended to validate a complementary clinician‐report version of the questionnaire:the SPARQ‐C.Methods: A sample of licensed mental health clinicians (N = 151) completed the SPARQ‐C along with other measures. Dataanalysis involved exploratory and confirmatory factor analyses (CFA). Reliability and convergent and criterion‐related validityof the SPARQ‐C were also evaluated.Results: The SPARQ‐C preserved the two‐factor structure: positive affect (k = 4, ω total = 0.84) and negative affect (k = 4, ωtotal = 0.70), which correlated r = 0.26. CFA using the a priori model two‐factor model based on the patient‐report versionprovided the following fit indices: χ2[19] = 26.01, CFI = 0.98; TLI = 0.97, RMSEA = 0.05 (90% CI [0.00, 0.09]), and SRMR = 0.05.The SPARQ‐C scales demonstrated convergent and criterion‐related validity with measures of other elements of the therapeuticrelationship, session outcome, and demographic‐clinical variables.Discussion: The SPARQ‐C is a reliable measure suitable for both clinical and research purposes. It allows for a nuancedassessment of patients' session‐level affective responses towards their therapist from the clinician's perspective.
The comparison of functional connectivity in Parkinson’s Disease patients with and without Parkin gene mutations
(Turkish Neuropsychiatric Society, 2025-06-19) Çebi, Merve; Ay, Ulaş; Kıçik, Ani; Erdoğdu, Emel; Tepgeç, Fatih; Uyguner, Zehra Oya; Tüfekçioğlu, Zeynep; Samancı, Bedia; Bilgiç, Başar; Emre, Murat; Demiralp, Tamer; Hanağası, Haşmet Ayhan
Introduction: Mapping the functional connectivity of brain regions became appealing in recent research in neurology. Accordingly, a growing body of evidence shows resting-state functional connectivity (rsFC) changes in neurodegenerative disorders including Parkinson’s Disease (PD). As characterised by extensive and progressive dopaminergic loss in the substantia nigra, PD emerges with serious motor and non-motor dysfunctions. In the literature, the minority of PD cases have been associated with certain genetic mutations. The aim of this study was to investigate the rsFC in a group of PD patients having Parkin gene mutation. Method: Twelve PD patients with Parkin mutation (PP-PD), 12 PD patients without Parkin mutation (PN-PD) and 12 healthy controls (HC) were included in the study. All participants underwent a resting-state functional magnetic resonance imaging as well as a neuropsychological assessment and clinical examination. Results: Results indicated that PP-PD had longer disease duration, a higher rate of dyskinesia and lower scores on complex visual perception tests. The resting state networks showed that all PD (consisting of PP-PD and PN-PD) and PP-PD groups had increased functional connectivity in the frontoparietal network as compared to the HC. In addition, the PP-PD group displayed decreased functional connectivity in the dorsal attention network compared to the PN-PD. Conclusion: In conclusion, our data suggests that PD with Parkin gene mutation might be emerging with distinct resting state functional connectivity changes in the brain.
Investigation of symptom-specific functional connectivity patterns in Parkinson’s disease
(Springer-Verlag Italia S.R.L., 2025-06-14) Kıçik, Ani; Bayram, Ali; Erdoğdu, Emel; Kurt, Elif; Sarıdede, Dilek Betül; Cengiz, Sevim; Bilgiç, Başar; Hanağası, Haşmet; Öztürk Işık, Esin; Gürvit, Hakan; Tüzün, Erdem; Demiralp, Tamer
Parkinson’s disease (PD) is a complex neurodegenerative disease, characterized by pronounced heterogeneity in symptoms. This study investigates the functional connectivity (FC) patterns associated with distinct symptom clusters, aiming to elucidate the heterogeneity in PD and uncover the neural mechanisms underlying its motor and cognitive symptoms. Resting-state functional MRI (rs-fMRI) data from 55 non-demented PD patients and 24 healthy controls (HC) were used to perform seed-to-seed FC analyses. A clustering algorithm was applied to the cognitive and motor scores of all PD patients to generate relatively homogeneous symptomatic subgroups. PD patients exhibited a general decrease in FC within a network comprising the sensorimotor network (SMN) and the visual network (VN) regions. Symptom-based clustering revealed three relatively homogeneous subgroups, exhibiting a gradient pattern: patients with greater motor deficits showed significant disconnection within the SMN, whereas patients with greater visuospatial deficits exhibited reduced FC in an extended subnetwork, with pronounced disconnections between the VN and SMN areas. Our study demonstrated a notable disconnection between the SMN and VN, indicating impaired visual-motor integration in PD. Stronger disconnection within the SMN was associated with greater motor dysfunction, and stronger visual-sensorimotor disconnections were associated with greater visuospatial deficits. These findings suggest that at least two separate routes of functional disconnection may be responsible for the inhomogeneous symptom distribution in PD.

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